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Chronic Lymphocytic Leukemia clinical trials in Washington, DC

22 studies for Chronic Lymphocytic Leukemia are looking for participants at sites in and around Washington (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

RecruitingPhase 1/2
  • American Oncology Partners of Maryland Pa, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05006716

A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).

RecruitingPhase 3
  • Center for Cancer and Blood Disorders ( Site 5439), Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05947851

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

RecruitingObservational study
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 110 · All sexes · Updated Oct 2, 2026 · NCT05724121

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • MedStar Georgetown University Hospital, Washington D.C.
  • MedStar Washington Hospital Center, Washington D.C.
  • Walter Reed National Military Medical Center, Bethesda · 7 mi away
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

RecruitingPhase 3
  • Sibley Memorial Hospital, Washington D.C.
  • Walter Reed National Military Medical Center, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT04269902

A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

RecruitingPhase 3
  • Medstar Georgetown University Hospital, Washington D.C.
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06973187

Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)

RecruitingObservational study
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 110 · All sexes · Updated Sep 28, 2026 · NCT00923507

Early Clonal Dynamics During Venetoclax Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

RecruitingPhase 2
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT03986034

Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment

RecruitingObservational studyHealthy volunteers welcome
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT01087333

Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies

RecruitingPhase 3
  • American Oncology Partners, PA dba The Center for Cancer and Blood Disorders, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07648264

A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

RecruitingPhase 2
  • Maryland Oncology Hematology, Silver Spring · 7 mi away
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07221500

Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib

RecruitingEarly phase 1
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 100 · All sexes · Updated Aug 21, 2026 · NCT07428707

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

RecruitingPhase 3
  • American Oncology Partners of Maryland, PA, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05254743

ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL

RecruitingPhase 3
  • The Center for Cancer and Blood Disorders-Bethesda, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT07342478

Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias

RecruitingPhase 1/2
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 120 · All sexes · Updated Jul 16, 2026 · NCT06364423

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

RecruitingPhase 1
  • National Institute of Health, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT05131022

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

RecruitingPhase 2
  • American Oncology Partners, PA, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated May 19, 2026 · NCT06588478

Cancer Experience Registry (CER) for Cancer Patients and Caregivers

RecruitingObservational studyHealthy volunteers welcome
  • Cancer Support Community Research & Training Institute, Washington D.C.
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT02333604

A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)

RecruitingPhase 3
  • Maryland Oncology Hematology - Silver Spring /ID# 267557, Silver Spring · 7 mi away
  • Center for Cancer and Blood Disorders-American Oncology Partners of Maryland /ID# 266445, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06428019

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

RecruitingPhase 1
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT04830137

Chronic Lymphocytic Leukemia trials in other cities

Other studies in Washington

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.