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Colorectal Cancer clinical trials in Iowa

15 studies for Colorectal Cancer are looking for participants at sites in Iowa.

Cities in Iowa

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

  • UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny
  • University of Iowa Healthcare Cancer Services Quad Cities, Bettendorf
  • Mercy Cancer Center-West Lakes, Clive
  • and 8 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05673148

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Mary Greeley Medical Center, Ames
  • McFarland Clinic - Ames, Ames
  • UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny
  • and 12 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Family Communications After Genetic Testing

  • Mercy Cancer Center-West Lakes, Clive
  • Mercy Medical Center - Des Moines, Des Moines
  • Mercy Medical Center-West Lakes, West Des Moines
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

  • University of Iowa Hospitals and Clinics, Iowa City
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06324357

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

  • University of Iowa Hospitals and Clinics, Iowa City
  • Mission Cancer Blood, Waukee
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06750094

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

  • University of Iowa Hospital, Iowa City
  • Mission Cancer Blood, Waukee
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06662786

Zanzalintinib Alone or in Combination With Pembrolizumab and Berahyaluronidase Alfa in Participants With Colorectal Cancer With Molecular Residual Disease

  • Oncology Hematology West, PC dba Nebraska Cancer Specialists - Council Bluffs, Council Bluffs
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07750158

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

  • University of Iowa Hospital and Clinics, Iowa City
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

  • University of Iowa Health Care, Iowa City
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05283330

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

  • University of Iowa Hospitals & Clinics, Iowa City
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT06026410

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

  • UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny
  • Saint Anthony Regional Hospital, Carroll
  • Physicians' Clinic of Iowa PC, Cedar Rapids
  • and 15 more
RecruitingPhase 3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

  • UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny
  • University of Iowa Healthcare Cancer Services Quad Cities, Bettendorf
  • Physicians' Clinic of Iowa PC, Cedar Rapids
  • and 10 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

  • The University of Iowa - Ankeny, Ankeny
  • Saint Anthony Regional Hospital, Carroll
  • Physicians' Clinic of Iowa PC, Cedar Rapids
  • and 8 more
RecruitingObservational study
Ages 60 and older · All sexes · Updated Jan 8, 2026 · NCT03998202

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.