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Glioma clinical trials in Washington, DC

19 studies for Glioma are looking for participants at sites in and around Washington (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

RecruitingPhase 1/2
  • Children's National Medical Center, Washington D.C.
12 Months – 21 Years · All sexes · Updated Oct 1, 2026 · NCT05099003

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

RecruitingPhase 1/2
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 99 · All sexes · Updated Sep 28, 2026 · NCT07416188

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

RecruitingPhase 2
  • Johns Hopkins Sibley Memorial Hospital, Washington D.C.
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

RecruitingPhase 2
  • Children's National Medical Center, Washington D.C.
12 Months – 39 Years · All sexes · Updated Sep 21, 2026 · NCT06838676

NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors

RecruitingPhase 1
  • Children's National Hospital, Washington D.C.
Ages 3 to 25 · All sexes · Updated Sep 9, 2026 · NCT07664176

Targeted Pediatric High-Grade Glioma Therapy

RecruitingObservational study
  • Children's National Medical Center, Washington D.C.
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379

Study of Olutasidenib and Temozolomide in HGG

RecruitingPhase 2
  • Children's National Medical Center, Washington D.C.
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

RecruitingPhase 1/2
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 15 and older · All sexes · Updated Aug 28, 2026 · NCT05588141

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

RecruitingPhase 2
  • Children's National Medical Center, Washington D.C.
Ages 3 to 39 · All sexes · Updated Aug 24, 2026 · NCT05096481

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

RecruitingPhase 1
  • Children's National Medical Center, Washington D.C.
Ages 1 to 25 · All sexes · Updated Aug 18, 2026 · NCT04485559

Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

RecruitingPhase 1
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 120 · All sexes · Updated Aug 14, 2026 · NCT06344130

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

RecruitingPhase 1/2
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 120 · All sexes · Updated Aug 12, 2026 · NCT06161519

MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas

RecruitingPhase 1/2
  • Children's National Hospital, Washington D.C.
Ages 1 to 26 · All sexes · Updated Jul 10, 2026 · NCT06712875

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

RecruitingEarly phase 1Healthy volunteers welcome
  • Children's National Medical Center, Washington D.C.
Ages 1 to 21 · All sexes · Updated Jun 29, 2026 · NCT06333899

A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

RecruitingPhase 1
  • Children's National Hospital, Washington D.C.
Ages 4 and older · All sexes · Updated Jun 25, 2026 · NCT04573140

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

RecruitingPhase 2
  • Children's National Medical Center, Washington D.C.
12 Months – 39 Years · All sexes · Updated May 29, 2026 · NCT05843253

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

RecruitingPhase 1/2
  • Sibley Memorial Hospital, Washington D.C.
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

RecruitingEarly phase 1
  • Children's National Medical Center, Washington D.C.
Up to age 21 · All sexes · Updated Mar 18, 2026 · NCT04655404

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

RecruitingPhase 1
  • National Institutes of Health, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Dec 18, 2025 · NCT04541082

Glioma trials in other cities

Other studies in Washington

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.