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Parkinson's Disease clinical trials in California
36 studies for Parkinson's Disease are looking for participants at sites in California.
Cities in California
- San Francisco14 studies
- Los Angeles10 studies
- Mountain View9 studies
- San Diego6 studies
- Sacramento3 studies
- Irvine3 studies
- Huntington Beach3 studies
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
- Neuro-Pain Medical Center, Fresno
- University of California, Irvine, Irvine
- University of California, Los Angeles, Los Angeles
- and 2 more
RecruitingPhase 2
Ages 40 to 80 · All sexes · Updated Oct 2, 2026 · NCT06680830A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease
- Site-003, Irvine
- Site-041, Los Angeles
RecruitingPhase 2/3
Ages 40 to 80 · All sexes · Updated Sep 28, 2026 · NCT06976268GBPDC: Gut-Brain in PD Consortium Master Protocol
- Stanford University, Stanford
RecruitingObservational studyHealthy volunteers welcome
Ages 21 to 80 · All sexes · Updated Sep 25, 2026 · NCT07567794A Study of Buntanetap in Participants With PD
- Parkinson's & Movement Disorder Institute (PMDI) - Orange County Office, Fountain Valley
RecruitingPhase 2/3
Ages 40 to 85 · All sexes · Updated Sep 21, 2026 · NCT07284784Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease
- The Parkinson's & Movement Disorder Institute, Fountain Valley
RecruitingPhase 2
Ages 40 to 80 · All sexes · Updated Sep 21, 2026 · NCT07005180Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
- Cedars Sinai Medical Center, Los Angeles
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT02071134Automated Daytime Adaptive Deep Brain Stimulation Parameter Optimization in Patients Implanted With Percept Neurostimulator
- University of California San Francisco, San Francisco
Recruiting
Ages 25 to 75 · All sexes · Updated Sep 14, 2026 · NCT07682311Dual Frequency Stimulation in Parkinson's Disease
- UC Davis Health, Sacramento
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04650932Simplified, Scalable, 24-hour Adaptive DBS in Parkinson's Disease
- University of California San Francisco, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07398157A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy
- Vima Site #048, Murrieta
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 11, 2026 · NCT07804615A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
- Profound Research LLC (Site #222), Carlsbad
- Collaborative Neuroscience Network - Los Alamitos- CenExel - PPDS (Site #217), Los Alamitos
- Keck Medicine of USC - USC Healthcare Center 2 (Site #221), Los Angeles
- and 1 more
RecruitingPhase 2
Ages 30 to 80 · All sexes · Updated Sep 10, 2026 · NCT07432958Parkinson Progression Marker Initiative Online (PPMI Online)
- UCSF Movement Disorders and Neuromodulation Center (MDNC), San Francisco
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05065060Parkinson's Foundation PD GENEration Genetic Registry
- University of California San Diego (UCSD), La Jolla
- University of Southern California, Los Angeles
- University of California Los Angeles, Los Angeles
- and 2 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04994015A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
- The Parkinson's & Movement Disorder Institute, Fountain Valley
- Keck School of Medicine, Los Angeles
RecruitingObservational study
Ages 45 to 75 · All sexes · Updated Sep 4, 2026 · NCT07330258Deep Brain Stimulation (DBS) Retrospective Outcomes Study
- Riverside University Health System, Moreno Valley
- University of California, San Francisco, San Francisco
RecruitingObservational study
All ages · All sexes · Updated Sep 3, 2026 · NCT03664609A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
- Neurology Center of North Orange County, Fullerton
- UC San Diego, La Jolla
- Keck School of Medicine of USC, Los Angeles
- and 5 more
RecruitingPhase 3
Ages 50 to 85 · All sexes · Updated Sep 3, 2026 · NCT07174310Optimizing Adaptive DBS for Parkinson's Disease
- UC Davis Center for Neuroscience, Davis
Recruiting
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07798271Transplantation of Human iPS Cell-derived Dopaminergic Progenitors (CT1-DAP001) for Parkinson's Disease (Phase I/II)
- University of California, San Diego, La Jolla
RecruitingPhase 1
Ages 40 to 75 · All sexes · Updated Aug 17, 2026 · NCT06482268Blood Pressure Effects on Cognition and Brain Blood Flow in PD
- University of California San Diego, San Diego
Recruiting
Ages 50 and older · All sexes · Updated Aug 7, 2026 · NCT05400174Psilocybin Therapy for Depression in Parkinson's Disease
- University of California, San Francisco, San Francisco
RecruitingPhase 2
Ages 40 to 80 · All sexes · Updated Aug 7, 2026 · NCT06455293A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease
- UCLA NeuroTranslational Research Center, Los Angeles
- UCI Medical Center - Neurology, Orange
- Stanford Neuroscience Health Center, Palo Alto
RecruitingPhase 3
Ages 45 to 75 · All sexes · Updated Aug 4, 2026 · NCT06944522Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease
- The Regenesis Project, Santa Monica
Recruiting
Ages 22 to 80 · All sexes · Updated Jul 31, 2026 · NCT07207122PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
- University of California San Diego, La Jolla
- Keck School of Medicine of USC, Los Angeles
- University of California, San Francisco, San Francisco
RecruitingObservational studyHealthy volunteers welcome
Ages 30 and older · All sexes · Updated Jul 27, 2026 · NCT04477785Effects of Accelerated rTMS On Motor and Cognitive Function in Parkinson's Disease
- San Francisco Neurology and Sleep Center, San Francisco
Recruiting
Ages 50 to 90 · All sexes · Updated Jun 16, 2026 · NCT07554833Understanding Motivation in Parkinson's Patients Through Neurophysiology
- University of California San Francisco, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Jun 5, 2026 · NCT05065151Use of CereGate Therapy for Freezing of Gait in PD
- Kaiser Permanente, KPNC Comprehensive Movement Disorders Program, Redwood City
Recruiting
Ages 21 to 80 · All sexes · Updated May 28, 2026 · NCT05292794A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease
- Collaborative Neuroscience Network - CNS, Los Alamitos
- Collaborative Neuroscience Network - CNS, Los Alamitos
RecruitingPhase 1Healthy volunteers welcome
Ages 30 to 85 · All sexes · Updated Apr 20, 2026 · NCT06809400Ketamine for Veterans With Parkinson's Disease
- San Francisco VA Medical Center, San Francisco, CA, San Francisco
RecruitingPhase 2
Ages 40 to 80 · All sexes · Updated Apr 13, 2026 · NCT06231563Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183A
- University of California, San Francisco
RecruitingEarly phase 1
Ages 40 to 85 · All sexes · Updated Dec 23, 2025 · NCT06932809Safety and Usability of the Cionic Neural Sleeve for Parkinson's Disease
- Adapt Movement, Carlsbad
- CIONIC, San Francisco
Recruiting
Ages 22 to 75 · All sexes · Updated Dec 18, 2025 · NCT07284823Real-World Patient Experiences Using Continuous Subcutaneous Apomorphine Infusion (ONAPGOTM) in the United States:
- Parkinson's Disease and Movement Disorders Center - Orange County (South), Aliso Viejo
- Parkinson's Disease and Movement Disorders Center - Orange County (North), Irvine
- Parkinson's Research Centers of America - Palo Alto, Palo Alto
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 22, 2025 · NCT07219927A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease
- Parkinson's Research Centers of America - Orange County, Aliso Viejo
- Parkinson's Research Centers of America - Palo Alto, Palo Alto
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Aug 24, 2025 · NCT06765668Evaluation of Neurocognitive Changes in Parkinson's Disease After Low Frequency Burst Stimulation
- University of Southern California Keck School of Medicine, Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Jun 11, 2025 · NCT05307055Combined STN and NBM Deep Brain Stimulation for Mild Cognitive Impairment in Parkinson's Disease
- Stanford Neuroscience Health Center, Stanford
Recruiting
Ages 21 to 80 · All sexes · Updated May 30, 2025 · NCT05968703Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
- UCSF, San Francisco
- Stanford University, Stanford
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 to 80 · All sexes · Updated May 2, 2025 · NCT05395624Real-Time Levodopa Level Monitoring in Parkinson Disease
- University of California San DIego, San Diego
Recruiting
Ages 40 to 85 · All sexes · Updated Feb 11, 2025 · NCT04735627From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.