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Sickle Cell Disease clinical trials in Tennessee

22 studies for Sickle Cell Disease are looking for participants at sites in Tennessee.

Cities in Tennessee

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

  • University of Tennessee Health Science Center, Memphis
  • St. Jude Children's Res Hosp, Memphis
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Sep 17, 2026 · NCT06612268

Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease

  • St. Jude Children's Research Hospital, Memphis
RecruitingPhase 1
Ages 8 to 17 · All sexes · Updated Sep 9, 2026 · NCT07226219

SCD Stem Cell Mobilization and Apheresis Using Motixafortide

  • St. Jude Children's Research Hospital, Memphis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06442761

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

  • St. Jude Children's Research Hospital, Memphis
  • Vanderbilt University Medical Center, Nashville
RecruitingObservational study
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Gene Therapy Communication: Use of a Needs Assessment to Drive Decision-AIDS for Gene Therapy for Rare Diseases (GENETX)

  • St. Jude Children's Research Hospital, Memphis
RecruitingObservational studyHealthy volunteers welcome
Ages 8 and older · All sexes · Updated Aug 10, 2026 · NCT05810181

Cooperative Assessment of Late Effects for SCD Curative Therapies

  • Vanderbilt University Medical Center, Nashville
RecruitingObservational study
Ages 4 to 65 · All sexes · Updated Jul 27, 2026 · NCT05153967

Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease

  • St Jude Children's Research Hospital, Memphis
RecruitingPhase 2
Up to age 22 · All sexes · Updated Jul 23, 2026 · NCT07616154

Peripheral Arterial Tonometry and Neurocognition in Sickle Cell Disease

  • St. Jude Children's Research Hospital, Memphis
RecruitingObservational study
Ages 12 to 25 · All sexes · Updated Jun 29, 2026 · NCT06477289

Investigation of the Genetics of Hematologic Diseases

  • St. Jude Children's Research Hospital, Memphis
RecruitingObservational study
All ages · All sexes · Updated Jun 9, 2026 · NCT02720679

Sickle Cell Clinical Research and Intervention Program

  • Regional One Health, Diggs-Kraus Sickle Cell Center, Memphis
  • Methodist Adult Comprehensive Sickle Cell Center, Memphis
  • St. Jude Children's Research Hospital, Memphis
RecruitingObservational study
All ages · All sexes · Updated Jun 4, 2026 · NCT02098863

Functional Ovarian Reserve in Sickle Cell Disease

  • St. Jude Children's Research Hospital, Memphis
RecruitingObservational studyHealthy volunteers welcome
Ages 10 to 18 · Women · Updated Jun 4, 2026 · NCT07392216

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

  • St Jude Children Hospital (NT-DMT), Memphis
  • St. Jude Children's Research Hospital (MRD-HCT), Memphis
RecruitingObservational study
Ages 3 to 20 · All sexes · Updated Jun 4, 2026 · NCT06941389

Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease

  • St. Jude Children's Research Hospital, Memphis
Recruiting
Ages 6 to 25 · All sexes · Updated May 18, 2026 · NCT03353584

Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET

  • St. Jude Children's Research Hospital, Memphis
RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 21 · All sexes · Updated May 6, 2026 · NCT05583721

Gene Editing For Sickle Cell Disease

  • St. Jude Children's Research Hospital, Memphis
RecruitingPhase 1
Ages 18 to 24 · All sexes · Updated May 5, 2026 · NCT06506461

Sickle Cell Disease and the Genomic and Gene Therapy Needs of Stakeholders

  • St. Jude Children's Research Hospital, Memphis
RecruitingObservational studyHealthy volunteers welcome
Ages 13 and older · All sexes · Updated May 1, 2026 · NCT04416178

School Readiness Intervention for Preschool Children With Sickle Cell Disease

  • St. Jude Children's Research Hospital, Memphis
Recruiting
42 Months – 78 Months · All sexes · Updated Apr 24, 2026 · NCT06367192

Delivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease

  • Vanderbilt University, Nashville
Recruiting
Ages 18 and older · All sexes · Updated Mar 23, 2026 · NCT06919224

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

  • TriStar Medical Group Children's Specialists - Pediatric Oncology, Nashville
RecruitingPhase 3
Ages 12 to 35 · All sexes · Updated Mar 23, 2026 · NCT05477563

A Long-term Follow-up Study in Patients Who Received BEAM-101

  • St. Jude Children's Research Hospital, Memphis
  • The Children's Hospital at TriStar Centennial, Nashville
RecruitingObservational study
Ages 14 to 37 · All sexes · Updated Jan 28, 2026 · NCT07373639

HPC Offered for PRESERVE Expansion

  • Tristar Centennial Medical Center, Nashville
RecruitingObservational study
Ages 12 to 80 · All sexes · Updated Aug 28, 2025 · NCT07145411

Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease

  • University of Tennessee at Memphis, Memphis
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 22, 2025 · NCT06385886

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.