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Cancer (all types) clinical trials in South Carolina
29 studies for Cancer (all types) are looking for participants at sites in South Carolina.
Cities in South Carolina
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
- Medical University of South Carolina, Florence
- Medical University of South Carolina Health Lancaster Medical Center, Lancaster
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 25, 2026 · NCT05920356A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
- Prisma Health, Greenville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06150157TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
- SC Cancer Specialists at St. Joseph's/Candler Bluffton, Bluffton
- St. Joseph's/Candler Smith, Bluffton
- Summit Cancer Care at St. Josph's/Candler Bluffton, Bluffton
- and 1 more
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)
- Medical University of South Carolina Hollings Cancer Center, Charleston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07227610Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
- Hematology and Oncology Associates of SC, LLC, Greenville
RecruitingPhase 2/3
All ages · All sexes · Updated Sep 18, 2026 · NCT03435796(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
- MUSC Health University Medical Center, Charleston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04996875Evaluating the Communication Between Patients and Providers in Cancer Clinics
- Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06985953The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials
- Saint Joseph's/Candler - Bluffton Campus, Bluffton
- South Carolina Cancer Specialists PC, Hilton Head Island
- The Radiation Oncology Center-Hilton Head/Bluffton, Hilton Head Island
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06756607A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- Medical University of South Carolina, Charleston
- Prisma Health Cancer Institute, Greenville
- Lexington Medical Center, West Columbia
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581Project: Every Child for Younger Patients With Cancer
- Medical University of South Carolina, Charleston
- Prisma Health Richland Hospital, Columbia
- BI-LO Charities Children's Cancer Center, Greenville
- and 2 more
RecruitingObservational study
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244Efficacy and Safety of Intravesical TARA-002 Compared With Investigator's Choice of Intravesical Chemotherapy in Participants With BCG-naïve High-grade Non-muscle Invasive Bladder Cancer
- START - Carolinas, Myrtle Beach
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT07480356Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
- Gibbs Cancer Center-Gaffney, Gaffney
- Gibbs Cancer Center-Pelham, Greer
- Spartanburg Medical Center, Spartanburg
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
- Prisma Health Cancer Institute, Greenville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144Optimizing Care for Cancer Survivors With Depression: Project 3
- Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06930729A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)
- Carolina Urologic Research Center, the START Center for Cancer Research, Myrtle Beach
RecruitingPhase 1
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT07103018Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors
- Medical University of South Carolina Hollings Cancer Center, Charleston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT07149207Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
- Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
- Wm. Jennings Bryan Dorn VA Medical Center, Columbia, SC, Columbia
Recruiting
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD)
- GSK Investigational Site, Myrtle Beach
RecruitingPhase 1
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06551142IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment)
- Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06582784An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors
- Prisma Health-Upstate, Greenville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06487624Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors
- Medical University of South Carolina (MUSC), Charleston
- PRISMA Health, Institute for Translational Oncology, Greenville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06014658Prevent Cancer- Greenville
- Prisma Health-Upstate, Greenville
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT04947098GEMINI-NSCLC: NSCLC Biomarker Study
- The Medical University of South Carolina, Charleston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05236114Beat Childhood Cancer Specimen Banking and Data Registry
- Medical University of South Carolina, Charleston
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Feb 3, 2026 · NCT04715178Reducing Metabolic Dysregulation in Dyads
- University of South Carolina, Columbia
RecruitingHealthy volunteers welcome
Ages 9 to 55 · All sexes · Updated Jan 29, 2026 · NCT06117241Caris Biorepository Research Protocol
- Clinical Biotechnology Research Institute at RSFH, Charleston
- Spartanburg Regional Health Services, Spartanburg
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT01499394SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Greenville
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774A Prospective Real World Evidence Study (PROWES) for Concordance Rate of Blood-based 3D Genome Conformation Mapping (Episwitch CiRT®) to Identify Likelihood of Response and Actual Response Rates to PD-(L)-1 Checkpoint Inhibitors Across Multiple Oncological Indications.
- Carolina Blood and Cancer Care Associates, Rock Hill
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2025 · NCT06635954Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
- Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.