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Liver Cancer (Hepatocellular Carcinoma) clinical trials in Los Angeles, CA

19 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in and around Los Angeles (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

RecruitingPhase 1/2
  • START Los Angeles, LLC, Los Angeles
  • Keck Hospital of USC, Los Angeles
  • Los Angeles General Medical Center, Los Angeles
  • and 3 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07227012

National Liver Cancer Screening Trial

RecruitingPhase 4
  • University of Southern California, Los Angeles
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06084234

Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

RecruitingPhase 1
  • USC Norris Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06915753

Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure

RecruitingPhase 2
  • USC Norris Comprehensive Cancer Center, Los Angeles
Ages 18 to 100 · All sexes · Updated Sep 23, 2026 · NCT07219459

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

RecruitingObservational study
  • Cedars-Sinai Medical Center, Los Angeles
Ages 22 and older · All sexes · Updated Sep 11, 2026 · NCT06486454

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

RecruitingPhase 3
  • Research Site, Los Angeles
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06921785

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

RecruitingPhase 1
  • University of Southern California, Los Angeles
  • Cedars-Sanai Medical Center - Samuel Oschin Comprehensive Cancer, Los Angeles
  • Cedars-Sanai Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Children's Hospital Los Angeles, Los Angeles
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • University of California, Los Angeles (UCLA), Los Angeles
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours

RecruitingPhase 1/2
  • Research Site, Los Angeles
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT06795022

A Study of MGC026 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • The Angeles Clinic and Research Institute, Los Angeles
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

RecruitingPhase 1/2
  • Los Angeles Cancer Network, Los Angeles
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064

ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma

RecruitingPhase 1/2
  • Children's Hospital Los Angeles, Los Angeles
Ages 1 to 21 · All sexes · Updated Jul 6, 2026 · NCT04634357

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

RecruitingPhase 1
  • Clinical Trial Site, Los Angeles
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06600321

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

RecruitingPhase 2
  • USA06-0, Los Angeles
  • USA16-0, Los Angeles
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06953089

A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

RecruitingPhase 1/2
  • Norris Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT05440708

Multilevel Determinants of Socioeconomic Disparities in Geographic Late-Stage Hepatocellular Carcinoma Hotspots

RecruitingObservational study
  • USC / Norris Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Jan 30, 2026 · NCT07312162

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 125, Los Angeles
  • Research Site 133, Los Angeles
  • Research Site 103, Los Angeles
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

Liver Cancer (Hepatocellular Carcinoma) trials in other cities

Other studies in Los Angeles

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.