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Liver Cancer clinical trials in California

24 studies for Liver Cancer are looking for participants at sites in California.

Cities in California

Distance-Based Exercise to Preserve Function and Prevent Disability

  • Kaiser Permanente Dublin, Dublin
  • Kaiser Permanente-Fremont, Fremont
  • Kaiser Permanente Fresno Orchard Plaza, Fresno
  • and 10 more
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

  • Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
  • UCI Health - Irvine Infusion Pharmacy ACC, Irvine
  • UCI Health - Irvine, Irvine
  • and 8 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07227012

DESTINY-PANTUMOUR04

  • Research Site, San Diego
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

National Liver Cancer Screening Trial

  • University of Southern California, Los Angeles
  • Stanford University, Redwood City
  • Kaiser Permanente, Roseville
  • and 1 more
RecruitingPhase 4
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06084234

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

  • City of Hope National Medical Center /ID# 270526, Duarte
  • City of Hope - Orange County Lennar Foundation Cancer Center /ID# 276120, Irvine
  • USC Norris Comprehensive Cancer Center /ID# 271573, Los Angeles
  • and 2 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06858813

CREO - Microwave Ablation Feasibility Study

  • Cedars Sinai, Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07817147

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

  • Providence St. Jude, Fullerton
  • Cedars-Sinai Medical Center, Los Angeles
  • Mission Hospital, Mission Viejo
  • and 3 more
RecruitingObservational study
Ages 22 and older · All sexes · Updated Sep 11, 2026 · NCT06486454

GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC

  • City of Hope, Duarte
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT04864054

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

  • USC/Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

  • Chao Family Comprehensive Cancer Center, University of California Irvine, Orange
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06580002

Multi-analyte Blood Test Clinical Trial

  • Gastroenterology and Liver Institute, Escondido
  • Providence Facey Medical Foundation, Mission Hills
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT05199259

A First in Human Study of PLT012 in Participants With Solid Tumor Cancers

  • USC Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT07337525

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

  • City of Hope Medical Center, Duarte
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06342414

ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma

  • Children's Hospital Los Angeles, Los Angeles
  • Children's Hospital Orange County, Orange
  • UCSF Benioff Children's Hospitals, San Francisco
RecruitingPhase 1/2
Ages 1 to 21 · All sexes · Updated Jul 6, 2026 · NCT04634357

Project for Multi-Omics-Based Early Detection of Hepatocellular Carcinoma (PROMETHEA Study)

  • City of Hope Medical Center, Duarte
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT07265271

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

  • Clinical Trial Site, La Jolla
  • Clinical Trial Site, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06600321

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

  • VA Long Beach Healthcare System, Long Beach, CA, Long Beach
  • VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto
  • VA Northern California Health Care System, Mather, CA, Sacramento
  • and 2 more
Recruiting
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

  • Start Lacn, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT07517198

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

  • Chao Family Comprehensive Cancer Center, University of California Irvine, Orange
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 3, 2026 · NCT07447050

Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma

  • University of California San Francisco, San Francisco
RecruitingPhase 2
Ages 0 to 30 · All sexes · Updated Feb 24, 2026 · NCT04134559

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

  • Cedars-Sinai Medical Center, Los Angeles
Recruiting
Ages 18 to 99 · All sexes · Updated Feb 20, 2026 · NCT04907643

REGULUS: MRI-guided Adaptive SABR for Liver Cancers

  • Stanford University, Palo Alto
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 9, 2026 · NCT07223307

Intra-procedural Spectral CT for Image-guided Embolization and Ablation in Interventional Oncology

  • VA Palo Alto Healthcare System, Palo Alto
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 26, 2025 · NCT07303725

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Duarte
  • Massive Bio SYNERGY-AI site, Irvine
  • Massive Bio SYNERGY-AI site, La Jolla
  • and 3 more
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.