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Non-Small Cell Lung Cancer clinical trials in Cicero, IL

24 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Cicero (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Edward Hines Jr VA Hospital, Hines · 4 mi away
  • Advocate Christ Medical Center, Oak Lawn · 9 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04267848

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Northwestern Medicine Oak Brook, Oak Brook · 9 mi away
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Hope and Healing Cancer Services, Hinsdale · 10 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC

RecruitingPhase 2
  • Hope and Healing Clinical Research, Hinsdale · 10 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07489066

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

RecruitingPhase 3
  • Advocate Christ Medical Center, Oak Lawn · 9 mi away
  • Hope and Healing Cancer Services, Hinsdale · 10 mi away
  • Endeavor Health, Elmhurst · 10 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06758401

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

RecruitingPhase 3
  • Affiliated Oncologists, LLC, Chicago Ridge · 10 mi away
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06561386

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

RecruitingPhase 3
  • Research Site, Hinsdale · 10 mi away
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06692738

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

RecruitingPhase 2/3
  • Loyola University Medical Center, Maywood · 5 mi away
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04613596

Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer

RecruitingPhase 3
  • Hope and Healing Cancer Services, Hinsdale · 10 mi away
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06899126

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

RecruitingPhase 3
  • Research Site, Hinsdale · 10 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07291037

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

RecruitingPhase 3
  • Research Site, Hinsdale · 10 mi away
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06350097

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

RecruitingPhase 3
  • Northwestern Medicine Oak Brook, Oak Brook · 9 mi away
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06686771

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

RecruitingPhase 3
  • Elmhurst Hospital Nancy Knowles Cancer Center, Elmhurst · 10 mi away
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06216301

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Rush MD Anderson Cancer Center at Rush Oak Park, Oak Park · 3 mi away
  • Edward Hines Jr VA Hospital, Hines · 4 mi away
  • Loyola University Medical Center, Maywood · 5 mi away
  • and 2 more
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

MYLUNG Consortium Part 3: Observational Study

RecruitingObservational study
  • Affiliated Oncologists, LLC, Chicago Ridge · 10 mi away
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT05885698

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Edward Hines Jr VA Hospital, Hines · 4 mi away
  • Loyola University Medical Center, Maywood · 5 mi away
  • Northwestern Medicine Oak Brook, Oak Brook · 9 mi away
  • and 3 more
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06116682

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Edward Hines Jr VA Hospital, Hines · 4 mi away
  • Loyola University Medical Center, Maywood · 5 mi away
  • Northwestern Medicine Oak Brook, Oak Brook · 9 mi away
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2/3
  • Loyola University Medical Center, Maywood · 5 mi away
  • Northwestern Medicine Oak Brook, Oak Brook · 9 mi away
  • Advocate Christ Medical Center, Oak Lawn · 9 mi away
  • and 2 more
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Advocate Christ Medical Center, Oak Lawn · 9 mi away
  • Advocate Outpatient Center - Oak Lawn, Oak Lawn · 9 mi away
  • Advocate High Tech Medical Park, Palos Heights · 12 mi away
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy

Recruiting
  • Edward Hines Jr. VA Hospital, Hines, IL, Hines · 4 mi away
Ages 18 and older · All sexes · Updated Feb 19, 2026 · NCT02984761

GEMINI-NSCLC: NSCLC Biomarker Study

RecruitingObservational study
  • Hope and Healing Cancer Services, Hinsdale · 10 mi away
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05236114

Non-Small Cell Lung Cancer trials in other cities

Other studies in Cicero

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.