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Triple-Negative Breast Cancer clinical trials in Pittsburgh, PA

11 studies for Triple-Negative Breast Cancer are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • University of Pittsburgh Medical Center, Pittsburgh
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy

Recruiting
  • University of Pittsburgh Cancer Institute (UPCI), Pittsburgh
Ages 30 and older · Women · Updated Sep 25, 2026 · NCT02945579

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

RecruitingPhase 1
  • UPMC, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07020117

Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

RecruitingPhase 2
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT03606967

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07029399

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07115043

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • Allegheny Health Network, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

ctDNA Positive Patients Diagnosed With cT1bN0 and cT1cN0 TNBC

RecruitingObservational study
  • UPMC Hillman Cancer, Pittsburgh
Ages 18 and older · Women · Updated May 1, 2026 · NCT07332975

Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab

RecruitingPhase 1/2
  • University of Pittsburgh Medical Center, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 29, 2025 · NCT06249048

Triple-Negative Breast Cancer trials in other cities

Other studies in Pittsburgh

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.