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Ovarian Cancer clinical trials in Pittsburgh, PA

30 studies for Ovarian Cancer are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

RecruitingPhase 2/3
  • UPMC Hillman Cancer Center, Pittsburgh
  • UPMC-Passavant Hospital, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07001748

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • UPMC-Magee Womens Hospital, Pittsburgh
  • UPMC Hillman Cancer Center, Pittsburgh
  • UPMC-Passavant Hospital, Pittsburgh
  • and 3 more
All ages · All sexes · Updated Oct 5, 2026 · NCT05564377

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • University of Pittsburgh Medical Center, Pittsburgh
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Distance-Based Exercise to Preserve Function and Prevent Disability

Recruiting
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

RecruitingPhase 1
  • Research Site, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05877599

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

RecruitingPhase 2
  • Western Pennsylvania Gynecologic Oncology /ID# 278632, Pittsburgh
Ages 18 and older · Women · Updated Sep 22, 2026 · NCT07059845

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Allegheny Health Network, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

RecruitingPhase 3
  • University of Pittsburgh Cancer Institute Cancer Services, Pittsburgh
  • Allegheny Health Network- West Penn Hospital, Pittsburgh
Ages 18 and older · Women · Updated Sep 15, 2026 · NCT07214779

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

RecruitingPhase 2
  • University of Pittsburgh Medical Center, Magee-Womens Hospital, Pittsburgh
  • West Penn Hospital of Allegheny Health Network, Pittsburgh
Ages 18 and older · Women · Updated Sep 14, 2026 · NCT06787612

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

RecruitingPhase 1/2
  • Allegheny Singer, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06303505

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

RecruitingPhase 1/2
  • Research Site, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT05123482

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 15 and older · All sexes · Updated Aug 25, 2026 · NCT06276491

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Children's Hospital of Pittsburgh of UPMC, Pittsburgh
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

RecruitingPhase 1
  • UPMC, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06774963

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Recruiting
  • Allegheny General Hospital, Pittsburgh
  • UPMC-Magee Womens Hospital, Pittsburgh
  • West Penn Hospital, Pittsburgh
  • and 5 more
Ages 35 to 50 · Women · Updated Aug 7, 2026 · NCT04251052

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • Allegheny Health Network, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers

RecruitingPhase 2
  • 127, Pittsburgh
Ages 18 and older · Women · Updated Jul 16, 2026 · NCT06906341

An Evaluation of Maintenance Therapy Combination Mirvetuximab Soravtansine and Olaparib

RecruitingPhase 2
  • UPMC Magee-Women's Hospital, Pittsburgh
Ages 18 to 100 · Women · Updated Jul 13, 2026 · NCT05887609

CPI-0209 Plus Carboplatin in Patients With Platinum Sensitive Recurrent Ovarian Cancer

RecruitingPhase 1
  • Magee-Womens Research Institute / UPMC Magee Womens Hospital, Pittsburgh
Ages 18 and older · Women · Updated Jul 8, 2026 · NCT05942300

Lead-212 PSV359 Therapy for Patients With Solid Tumors

RecruitingPhase 1/2
  • University of Pittsburgh Medical Center, Pittsburgh
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT06710756

ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer

RecruitingPhase 2
  • University of Pittsburgh Medical Center, Pittsburgh
Ages 18 and older · Women · Updated Jun 18, 2026 · NCT05071937

Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT04890613

ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

RecruitingPhase 1/2
  • University of Pittsburgh Medical Center, Pittsburgh
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT03686124

Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

RecruitingPhase 3
  • West Penn Hospital, Pittsburgh
  • Jefferson Hospital, Jefferson Hills · 11 mi away
  • Forbes Hospital, Monroeville · 11 mi away
  • and 1 more
Ages 18 and older · Women · Updated Apr 16, 2026 · NCT05659381

Heated Versus Aerosol-based Laparoscopic Chemotherapy for Cancer That Has Spread to the Peritoneum (Abdominal Lining)

RecruitingPhase 2
  • Allegheny Health Network West Penn Hospital, Pittsburgh
Ages 18 to 80 · All sexes · Updated Feb 27, 2026 · NCT07282834

About Ovarian Cancer

Ovarian cancer is a cancerous tumor that forms in the tissues of an ovary. The ovaries are a pair of female reproductive glands that make eggs and female hormones.

More about Ovarian Cancer on MedlinePlus

Ovarian Cancer trials in other cities

Other studies in Pittsburgh

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.