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Crohn's Disease clinical trials in New York City, NY

35 studies for Crohn's Disease are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

RecruitingPhase 2
  • New York Gastroenterology Associates - Upper East Side /ID# 281767, New York
Ages 18 to 75 · All sexes · Updated Oct 5, 2026 · NCT07697456

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

RecruitingPhase 1
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
  • NYP/Weill Cornell Medical Center, New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT03816345

Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)

RecruitingPhase 3
  • New York Gastroenterology Associates ( Site 0253), New York
All ages · All sexes · Updated Oct 2, 2026 · NCT06651281

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

RecruitingPhase 3
  • NYU Langone Health - Inflammatory Bowel Disease Center (IBD) ( Site 5078), New York
  • Weill Cornell Medical College, New-York Presbyterian Hospital ( Site 5079), New York
  • New York Gastroenterology Associates ( Site 5013), New York
Ages 16 to 80 · All sexes · Updated Oct 2, 2026 · NCT06430801

A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

RecruitingPhase 4
  • New York Gastroenterology Associates, New York
Ages 18 to 80 · All sexes · Updated Sep 30, 2026 · NCT06581328

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

RecruitingPhase 2
  • Northwell Health-Lenox Hill Hospital /ID# 265527, New York
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT06548542

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • Weill Cornell Medical College - Judith Jaffe Multiple Sclerosis Center, New York
  • Icahn School of Medicine at Mount Sinai, New York
Ages 2 to 17 · All sexes · Updated Sep 25, 2026 · NCT05923073

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2
  • Icahn School of Medicine at Mount Sinai (ISMMS) - The Mount Sinai Hospital (MSH), New York
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT06233461

A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • New York Gastroenterology Associates, New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07499232

A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2/3
  • Inflammatory Bowel Disease Center at NYU Langone, New York
  • Weill Cornell Medical College, New York
  • Lenox Hill Hospital, New York
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07196722

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

RecruitingPhase 3
  • New York Gastroenterology Associates, New York
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • Manhattan Clinical Research, LLC-Site Number: 8400069, New York
  • NYU Langone Health-Site Number: 8400091, New York
  • Columbia University Medical Center-Site Number: 8400138, New York
  • and 2 more
Ages 16 to 80 · All sexes · Updated Sep 23, 2026 · NCT07184931

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • NYU Langone Health-Site Number: 8400091, New York
  • Weill Cornell Medicine - NewYork-Presbyterian Hospital-Site Number: 8400040, New York
  • New York Gastroenterology Associates-Site Number: 8400009, New York
Ages 16 to 80 · All sexes · Updated Sep 23, 2026 · NCT07184944

A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • Icahn School of Medicine at Mount Sinai /ID# 254880, New York
Ages 2 to 17 · All sexes · Updated Sep 23, 2026 · NCT05995353

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

RecruitingPhase 3
  • Icahn School of Medicine at Mount Sinai, New York
Ages 2 to 19 · All sexes · Updated Sep 22, 2026 · NCT04844606

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

RecruitingPhase 4
  • NYU Langone Health, New York
Ages 18 to 70 · All sexes · Updated Sep 9, 2026 · NCT06045754

Standardized Microbiota Transplant Therapy in Crohn's Disease

RecruitingPhase 2
  • NYU Langone Health, New York
Ages 18 to 89 · All sexes · Updated Sep 8, 2026 · NCT06631586

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • New York Gastroenterology Associates, New York
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07577843

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

RecruitingPhase 3
  • Weill Cornell Medical College (WCMC) - Judith Jaffe Multiple Sclerosis Center (JJMSC), New York
  • Icahn School of Medicine at Mount Sinai, New York
  • Columbia University Medical Center/New York Presbyterian, New York
Ages 2 to 17 · All sexes · Updated Aug 24, 2026 · NCT05509777

Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease

RecruitingPhase 3
  • Weill Cornell Medicine, New York
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT06274554

Behavioral Therapy for Crohn's Disease

Recruiting
  • Icahn School of Medicine at Mount Sinai, New York
  • New York Gastroenterology Associates, New York
Ages 18 to 65 · All sexes · Updated Aug 12, 2026 · NCT06512597

Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

Recruiting
  • NYU Langone Health, New York
  • Cornell University, New York
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT05230173

Zymfentra (Infliximab-dyyb) REal World Cohort STudy

RecruitingObservational study
  • New York University, New York
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07237516

Low Dose IL-2 for the Treatment of Crohn's Disease

RecruitingPhase 1/2
  • Mount Sinai, New York
Ages 12 to 80 · All sexes · Updated Aug 3, 2026 · NCT04263831

Autologous Stem Cell Transplant for Crohn's Disease

RecruitingPhase 2
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT03219359

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • Icahn School of Medicine at Mount Sinai /ID# 262216, New York
Ages 2 to 17 · All sexes · Updated Jun 24, 2026 · NCT06332534

A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

RecruitingPhase 3
  • New York Presbyterian Hospital, New York
Ages 2 to 17 · All sexes · Updated Jun 22, 2026 · NCT06405087

Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease

RecruitingPhase 2
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 to 80 · All sexes · Updated Jun 5, 2026 · NCT06976853

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

RecruitingPhase 3
  • Columbia University Medical Center, New York-Presbyterian Hospital, New York
Ages 18 to 65 · All sexes · Updated May 27, 2026 · NCT06227910

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

RecruitingPhase 4
  • Columbia University Medical Center, New York
Ages 6 to 17 · All sexes · Updated May 27, 2026 · NCT05781152

Study of the Kono-S Anastomosis Versus the Side-to-side Functional End Anastomosis

Recruiting
  • Weill Cornell Medical College, New York
Ages 18 to 90 · All sexes · Updated May 14, 2026 · NCT03256240

A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

RecruitingPhase 2
  • Mirador Therapeutics Selected Site, New York
Ages 18 to 80 · All sexes · Updated Mar 12, 2026 · NCT07113522

Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation

RecruitingObservational studyHealthy volunteers welcome
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 and older · All sexes · Updated Jan 7, 2026 · NCT06001450

Treatment of Moderate to Severe Refractory Crohn's Disease

RecruitingPhase 1/2
  • Mount Sinai Health Systems, New York
Ages 18 to 65 · All sexes · Updated Dec 10, 2025 · NCT06721962

Helmsley 3.0: Abbreviated MRE

RecruitingObservational study
  • NYU Langone, New York
Ages 10 and older · All sexes · Updated Oct 27, 2025 · NCT06533228

About Crohn's Disease

Crohn's Disease can cause inflammation in any area from the mouth to the anus. Read about medicines, surgery or dietary management to treat symptoms.

More about Crohn's Disease on MedlinePlus

Crohn's Disease trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.