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Heart Diseases clinical trials in Pennsylvania

15 studies for Heart Diseases are looking for participants at sites in Pennsylvania.

Cities in Pennsylvania

ELEVATE-HFpEF Clinical Study

  • Lancaster General Hospital, Lancaster
  • Lankenau Institute for Medical Research, Wynnewood
Recruiting
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

  • UPMC Pinnacle Harrisburg Campus, Harrisburg
  • UPMC Presbyterian, Pittsburgh
  • Lankenau Medical Center, Wynnewood
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

  • Thomas Jefferson University Hospital, Philadelphia
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

  • Hospital of the University of Pennsylvania, Philadelphia
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489

Abbott Structural Heart Device Registry

  • University of Pennsylvania, Philadelphia
  • UPMC, Pittsburgh
RecruitingObservational study
All ages · All sexes · Updated Sep 1, 2026 · NCT06590467

Randomization of Single vs Multiple Arterial Grafts

  • Allegheny General Hospital (Cardiovascular Institute), Pittsburgh
Recruiting
Ages 18 to 70 · All sexes · Updated Aug 20, 2026 · NCT03217006

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

  • Penn Presbyterian Medical Center, Philadelphia
  • University of Pittsburgh Medical Center, Presbyterian Hospital, Pittsburgh
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure

  • University of Pennsylvania, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT06552637

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

  • Penn State Health, Hershey
  • UPMC, Pittsburgh
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

  • Abington Memorial Hospital, Abington
  • Penn State Milton S. Hershey Medical Center, Hershey
  • University of Pennsylvania, Philadelphia
  • and 1 more
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

  • Penn Medicine Lancaster General Health, Lancaster
  • UPMC Pinnacle Hospitals, Mechanicsburg
  • University of Pennsylvania, Philadelphia
  • and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

  • University of Pennsylvania, Philadelphia
  • Allegheny General Hospital, Pittsburgh
  • Lankenau Medical Center, Wynnewood
Recruiting
Ages 18 and older · Women · Updated Apr 1, 2026 · NCT04124120

Angiography and Electrogram Guided Bachmann Bundle Pacing

  • Geisinger Wyoming Valley, Wilkes-Barre
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 22, 2025 · NCT07110922

Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT)

  • Lancaster General Hospital, Lancaster
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jan 30, 2025 · NCT06688396

PARTNER 3 Trial - Aortic Valve-in-Valve

  • University of Pennsylvania Hospital, Philadelphia
  • Allegheny General Hospital, Pittsburgh
  • Lankenau Medical Center, Wynnewood
Recruiting
All ages · All sexes · Updated May 10, 2024 · NCT03003299

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.