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Heart Diseases clinical trials in Pittsburgh, PA

9 studies for Heart Diseases are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
  • UPMC Presbyterian, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Abbott Structural Heart Device Registry

RecruitingObservational study
  • UPMC, Pittsburgh
All ages · All sexes · Updated Sep 1, 2026 · NCT06590467

Randomization of Single vs Multiple Arterial Grafts

Recruiting
  • Allegheny General Hospital (Cardiovascular Institute), Pittsburgh
Ages 18 to 70 · All sexes · Updated Aug 20, 2026 · NCT03217006

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

RecruitingPhase 3
  • University of Pittsburgh Medical Center, Presbyterian Hospital, Pittsburgh
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • UPMC, Pittsburgh
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • Allegheny General Hospital, Pittsburgh
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Allegheny Health Network, Pittsburgh
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

Recruiting
  • Allegheny General Hospital, Pittsburgh
Ages 18 and older · Women · Updated Apr 1, 2026 · NCT04124120

PARTNER 3 Trial - Aortic Valve-in-Valve

Recruiting
  • Allegheny General Hospital, Pittsburgh
All ages · All sexes · Updated May 10, 2024 · NCT03003299

About Heart Diseases

Heart disease is the leading cause of death in the U.S. Learn about the different types of heart diseases, and what you can do to try to prevent them.

More about Heart Diseases on MedlinePlus

Heart Diseases trials in other cities

Other studies in Pittsburgh

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.