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Liver Cancer (Hepatocellular Carcinoma) clinical trials in Pittsburgh, PA

15 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Phase 1 Study of the Safety and Tolerability of CTX-10726

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07419841

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #32, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Upmc Hillman Cancer Center(Univ of Pittsburgh), Pittsburgh
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06427941

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

RecruitingPhase 3
  • Research Site, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06921785

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Children's Hospital of Pittsburgh of UPMC, Pittsburgh
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • University of Pittsburgh Medical Center, Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Molecular Basis of Pediatric Liver Cancer

RecruitingObservational study
  • UPMC Children's Hospital of Pittsburgh, Pittsburgh
Ages 0 to 99 · All sexes · Updated Aug 10, 2026 · NCT03959800

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

RecruitingPhase 2
  • Allegheny General Hospital, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05168163

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

RecruitingPhase 2
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT04114136

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

RecruitingPhase 1
  • Clinical Trial Site, Pittsburgh
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06600321

Patient Preference for Subcutaneous vs. Intravenous Immune Therapy

RecruitingPhase 2
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT07223424

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

RecruitingPhase 2
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Apr 2, 2026 · NCT05733598

Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies

RecruitingPhase 1/2
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT03539822

Zanzalintinib (XL-092) Plus Durvalumab and Tremelimumab in Unresectable Hepatocellular Carcinoma (ZENOBIA)

RecruitingPhase 2
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Nov 6, 2025 · NCT06698250

Liver Cancer (Hepatocellular Carcinoma) trials in other cities

Other studies in Pittsburgh

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.