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Breast Cancer clinical trials in Kansas City, MO

34 studies for Breast Cancer are looking for participants at sites in and around Kansas City (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Saint Luke's Hospital of Kansas City, Kansas City
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

RecruitingPhase 3
  • University of Kansas Cancer Center, Westwood · 5 mi away
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06982521

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

RecruitingPhase 3
  • HCA Midwest Division, Kansas City
Ages 18 to 100 · All sexes · Updated Oct 2, 2026 · NCT05827081

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Kansas City Veterans Affairs Medical Center, Kansas City
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

RecruitingPhase 2
  • Saint Luke's Cancer Institute, Kansas City
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06369285

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • St. Lukes Hospital of Kansas City, Kansas City
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

RecruitingPhase 3
  • The University of Kansas Cancer Center, Westwood · 5 mi away
Ages 60 and older · All sexes · Updated Sep 25, 2026 · NCT06377852

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

RecruitingPhase 3
  • Saint Luke's Cancer Institute ( Site 0059), Kansas City
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06966700

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

RecruitingPhase 3
  • Clinical Trial Site, Kansas City
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07085767

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Saint Luke's Cancer Institute, Kansas City
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

RecruitingPhase 3
  • Saint Luke's Hospital of Kansas City, Kansas City
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07173751

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • Saint Luke's Cancer Institute, Kansas City
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer

RecruitingPhase 2
  • HCA Midwest Division, Kansas City
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07368998

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3
  • University Health Truman Medical Center, Kansas City
  • University of Kansas Cancer Center - Briarcliff, Kansas City
  • University of Kansas Cancer Center - North, Kansas City
  • and 1 more
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926

Triple Negative Breast Cancer and Germline Hereditary Breast and Ovarian Cancer Mutation Carrier Registry

RecruitingObservational studyHealthy volunteers welcome
  • Universtiy Health, Kansas City
  • KCCC South, Kansas City
  • Research Medical Center, Kansas City
  • and 2 more
All ages · All sexes · Updated Aug 18, 2026 · NCT02302742

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

RecruitingPhase 3
  • University of Kansas Cancer Center - North, Kansas City
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • University of Kansas Medical Center (KUMC), Westwood · 5 mi away
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

HER2-positive Breast Cancer Registry

RecruitingObservational study
  • The University of Kansas Cancer Center, Westwood · 5 mi away
Ages 18 and older · All sexes · Updated Jul 17, 2026 · NCT06603597

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Saint Luke's Cancer Institute, Kansas City
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

Integrated Cancer Repository for Cancer Research

RecruitingObservational studyHealthy volunteers welcome
  • Saint Luke's Cancer Institute, East, Kansas City
  • Saint Luke's Cancer Institute, Kansas City
  • Saint Luke's Cancer Institute, Kansas City North, Kansas City
  • and 1 more
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

RecruitingPhase 3
  • Saint Luke's Cancer Institute, Kansas City
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT05696626

Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

RecruitingPhase 3
  • Saint Luke's Cancer Institute, Kansas City
  • The University of Kansas Cancer Center, Westwood · 5 mi away
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT06757634

Trial of Neoadjuvant THP vs TCHP for HER2-Amplified/Positive Breast Cancer

RecruitingPhase 2
  • The University of Kansas Cancer Center - North, Kansas City
  • KUCC - Briarcliff, Westwood · 5 mi away
  • KUCC - Olathe, Westwood · 5 mi away
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07220135

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • University of Kansas Cancer Center - Briarcliff, Kansas City
  • University of Kansas Cancer Center - North, Kansas City
  • University of Kansas Cancer Center at North Kansas City Hospital, North Kansas City · 2 mi away
  • and 1 more
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis

RecruitingPhase 1/2
  • The University of Kansas Cancer Center, Westwood · 5 mi away
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT06374459

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • University Health Truman Medical Center, Kansas City
  • University of Kansas Cancer Center - Briarcliff, Kansas City
  • University of Kansas Cancer Center - North, Kansas City
  • and 1 more
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

RecruitingObservational study
  • Saint Luke's Hospital of Kansas City, Kansas City
  • University of Kansas Cancer Center, Westwood · 5 mi away
Ages 18 and older · All sexes · Updated Jan 20, 2026 · NCT06401421

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Kansas City
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

RecruitingPhase 3
  • Truman Medical Centers, Kansas City
  • University of Kansas Cancer Center - North, Kansas City
  • University of Kansas Cancer Center at North Kansas City Hospital, North Kansas City · 2 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT03418961

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Kansas City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.