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Liver Cancer (Hepatocellular Carcinoma) clinical trials in St. Louis, MO

13 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Washington University School of Medicine, St Louis
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC

RecruitingPhase 1/2
  • Research Facility, St Louis
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06726161

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

RecruitingPhase 1/2
  • Siteman Cancer Center, St Louis
  • Barnes-Jewish Hospital, St Louis
  • Washington University School of Medicine - Siteman Cancer Center, St Louis
  • and 5 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07227012

A Study Evaluating a New Radiation Treatment Workflow (NGDS)

Recruiting
  • Siteman Cancer Center Washington University, St Louis
Ages 21 and older · All sexes · Updated Sep 17, 2026 · NCT07824583

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

RecruitingPhase 3
  • Research Site, St Louis
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06921785

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Washington University School of Medicine, St Louis
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

RecruitingPhase 3
  • Washington University School of Medicine, St Louis
  • Siteman Cancer Center-South County, St Louis
  • Siteman Cancer Center at Christian Hospital, St Louis
  • and 2 more
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07166406

First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours

RecruitingPhase 1/2
  • Research Site, St Louis
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT06795022

IDOV-Immune for Advanced Solid Tumors

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06910657

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

Recruiting
  • St. Louis VA Medical Center John Cochran Division, St. Louis, MO, St Louis
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572

A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

RecruitingPhase 1/2
  • Washington University in St. Louis, St Louis
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT05440708

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, St Louis
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Liver Cancer (Hepatocellular Carcinoma) trials in other cities

Other studies in St. Louis

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.