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Heart Failure clinical trials in St. Louis, MO
24 studies for Heart Failure are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.
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Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
RecruitingPhase 2/3
- Washington University-Pediatric Cardiology/ St. Louis Children's Hospital ( Site 0006), St Louis
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
RecruitingPhase 3
- St. Louis Heart and Vascular, P.C., St Louis
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
RecruitingPhase 3
- St. Louis Heart and Vascular, P.C., St Louis
INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery
Recruiting
- Barnes Jewish, St Louis
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
RecruitingObservational study
- St Louis, St Louis
A Study of LY3971297 in Participants With Heart Failure
RecruitingPhase 1
- Washington University, St Louis
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
RecruitingPhase 3
- Washington University Center for Advanced Medicine, St Louis
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
RecruitingPhase 3
- Washington University - St. Louis Children's Hospital - Cardiology, St Louis
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
RecruitingPhase 3
- Research Site, St Louis
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
RecruitingPhase 3
- Washington University - St. Louis Children's Hospital - Cardiology, St Louis
A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
RecruitingPhase 2
- Local Institution - 12, St Louis
Alleviant ALLAY-HFrEF Study
Recruiting
- Washington University - St Louis, St Louis
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
RecruitingPhase 2
- Washington University School of Medicine, St Louis
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
RecruitingPhase 3
- Research Site, Bridgeton · 15 mi away
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
RecruitingPhase 2
- Washington University Center for Advanced Medicine, St Louis
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
RecruitingObservational study
- Washington University, St Louis
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
RecruitingPhase 3
- Washington University, St Louis
- Amicis Centers of Clinical Research, St Louis
Alleviant ALLAY-HF Study
Recruiting
- Washington University - St Louis, St Louis
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
RecruitingPhase 3
- Washington Univ School Of Medicine, St Louis
The Inorganic Nitrate and eXercise Performance in Heart Failure (iNIX-HF)
RecruitingPhase 2
- Washington University School of Medicine, St Louis
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Recruiting
- St. Louis Heart and Vascular, St Louis
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
RecruitingPhase 3
- Washington University, St Louis
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
Recruiting
- Washington University - Barnes Jewish Health Hospital, St Louis
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
RecruitingPhase 1/2
- Washington University in Saint Louis, St Louis
About Heart Failure
Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.
More about Heart Failure on MedlinePlus
Heart Failure trials in other cities
- New York City, NY51 studies
- Boston, MA46 studies
- Dallas, TX42 studies
- Houston, TX35 studies
- Cleveland, OH31 studies
- Philadelphia, PA31 studies
- San Francisco, CA29 studies
- Chicago, IL28 studies
- Durham, NC25 studies
- Kansas City, MO25 studies
- Indianapolis, IN24 studies
- Atlanta, GA23 studies
Other studies in St. Louis
- Non-Small Cell Lung Cancer68 studies
- Breast Cancer63 studies
- Metastatic Cancer52 studies
- Cancer (all types)51 studies
- Colorectal Cancer51 studies
- Prostate Cancer45 studies
- Ovarian Cancer37 studies
- Lung Cancer37 studies
- Pancreatic Cancer33 studies
- Head and Neck Squamous Cell Carcinoma32 studies
- Endometrial Cancer29 studies
- Multiple Myeloma26 studies
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.