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Lung Cancer clinical trials in Sacramento, CA

22 studies for Lung Cancer are looking for participants at sites in and around Sacramento (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Kaiser Permanente Downtown Commons, Sacramento
  • Sutter Medical Center Sacramento, Sacramento
  • University of California Davis Comprehensive Cancer Center, Sacramento
  • and 1 more
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04267848

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

RecruitingPhase 3
  • Kaiser Permanente Downtown Commons, Sacramento
  • University of California Davis Comprehensive Cancer Center, Sacramento
  • Kaiser Permanente-South Sacramento, Sacramento
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04181060

Distance-Based Exercise to Preserve Function and Prevent Disability

Recruiting
  • Kaiser Permanente-South Sacramento, Sacramento
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Cancer Center - Sacramento, Sacramento
  • Woodland Memorial Hospital, Woodland · 16 mi away
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Kaiser Permanente Downtown Commons, Sacramento
  • University of California Davis Comprehensive Cancer Center, Sacramento
  • Kaiser Permanente-South Sacramento, Sacramento
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • UC Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

RecruitingPhase 1/2
  • University of California Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06287775

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

RecruitingPhase 1/2
  • University of California Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07012031

Patient-Derived Xenografts to Reduce Cancer Health Disparities

RecruitingObservational study
  • University of California Davis Comprehensive Cancer Center, Sacramento
Ages 21 to 100 · All sexes · Updated Aug 20, 2026 · NCT04410302

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Sutter Medical Center Sacramento, Sacramento
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • Xencor Investigative Site, Sacramento
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

RecruitingPhase 1/2
  • UC Davis, Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT06162221

Studying Tumor Tissue Samples and Blood Samples to Learn More About DNA Changes in Patients With Lung Cancer

RecruitingObservational study
  • University of California Davis Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT00899405

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Kaiser Permanente Downtown Commons, Sacramento
  • Sutter Medical Center Sacramento, Sacramento
  • University of California Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • University of California, Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2/3
  • Kaiser Permanente Downtown Commons, Sacramento
  • University of California Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Sutter Medical Center Sacramento, Sacramento
  • University of California Davis Comprehensive Cancer Center, Sacramento
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688

Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

RecruitingHealthy volunteers welcome
  • University of California, Davis · 14 mi away
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT06196008

Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer

RecruitingPhase 1
  • The University of California Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Feb 27, 2026 · NCT05452005

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • University of California Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer

RecruitingPhase 1/2
  • VA Northern California Health Care System, Mather, CA, Sacramento
Ages 18 and older · All sexes · Updated Jan 27, 2026 · NCT05467748

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Sacramento

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.