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Metastatic Cancer clinical trials recruiting in the U.S.
283 studies for Metastatic Cancer are recruiting participants at sites across the United States.
Cities with the most studies
- Houston, TX104 studies
- New York City, NY93 studies
- Nashville, TN70 studies
- Boston, MA63 studies
- Los Angeles, CA57 studies
- St. Louis, MO54 studies
- Arlington, VA53 studies
- Philadelphia, PA46 studies
- Chicago, IL45 studies
- San Antonio, TX44 studies
- Washington, DC43 studies
- Dallas, TX42 studies
- Seattle, WA39 studies
- Durham, NC33 studies
- Rochester, MN31 studies
- Pittsburgh, PA31 studies
- San Diego, CA30 studies
- Cleveland, OH30 studies
- Baldwin Park, CA30 studies
- Tampa, FL29 studies
- Denver, CO29 studies
- Orlando, FL29 studies
- Portland, OR29 studies
- Atlanta, GA28 studies
- Queens, NY28 studies
- San Francisco, CA28 studies
- Baltimore, MD28 studies
- Jacksonville, FL28 studies
- Columbus, OH27 studies
- Aurora, CO25 studies
- Mountain View, CA25 studies
- Detroit, MI24 studies
- Miami, FL24 studies
- New Haven, CT23 studies
- Grand Rapids, MI22 studies
- Madison, WI21 studies
- Salt Lake City, UT20 studies
- Phoenix, AZ20 studies
- Edison, NJ20 studies
- Orange, CA20 studies
By state
- Alabama13 studies
- Arizona46 studies
- Arkansas14 studies
- California130 studies
- Colorado50 studies
- Connecticut27 studies
- Delaware8 studies
- District of Columbia24 studies
- Florida91 studies
- Georgia34 studies
- Hawaii5 studies
- Idaho5 studies
- Illinois58 studies
- Indiana25 studies
- Iowa10 studies
- Kansas15 studies
- Kentucky17 studies
- Louisiana20 studies
- Maine9 studies
- Maryland47 studies
- Massachusetts65 studies
- Michigan51 studies
- Minnesota40 studies
- Mississippi6 studies
- Missouri59 studies
- Montana4 studies
- Nebraska15 studies
- Nevada10 studies
- New Hampshire11 studies
- New Jersey44 studies
- New Mexico13 studies
- New York111 studies
- North Carolina52 studies
- North Dakota5 studies
- Ohio62 studies
- Oklahoma16 studies
- Oregon29 studies
- Pennsylvania68 studies
- Rhode Island9 studies
- South Carolina14 studies
- South Dakota10 studies
- Tennessee75 studies
- Texas139 studies
- Utah31 studies
- Vermont4 studies
- Virginia66 studies
- Washington47 studies
- West Virginia6 studies
- Wisconsin34 studies
Recently updated studies
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
RecruitingPhase 2
All ages · All sexes · Updated Oct 2, 2026 · NCT05564377The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07562152Adding Spatially Fractionated Radiation Therapy to Standard Palliative Radiation for Improving Disease-Related Symptoms in Patients With Unresectable Solid Tumors
Recruiting
Ages 15 and older · All sexes · Updated Oct 2, 2026 · NCT07856394Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05372614A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07205822A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06234605A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
RecruitingPhase 1
Ages 19 and older · All sexes · Updated Oct 1, 2026 · NCT06586957A Study to Assess the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, Immunogenicity and Antitumour Activity of IPN60300 in Adults With Locally Advanced or Metastatic Solid Tumours
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07213817TLR9 Immunotherapy for Peritoneal Carcinomatosis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07658196Study of Orellanine in Metastatic Clear-Cell or Papillary Renal Cell Carcinoma
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05287945Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05222620PRE-ISPY Phase I/II Oncology Platform Program
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05868226A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091A Study of ASP3082 in Adults With Advanced Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05382559First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05875168Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06943755Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05803382Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413Parenting Support Intervention for Families Coping With Metastatic or Locally Recurrent Solid Tumor Diagnosis
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05059678A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
RecruitingPhase 1/2
Up to age 25 · All sexes · Updated Sep 25, 2026 · NCT04094610From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.