Home › Alzheimer's Disease › Pennsylvania
Alzheimer's Disease clinical trials in Pennsylvania
24 studies for Alzheimer's Disease are looking for participants at sites in Pennsylvania.
Cities in Pennsylvania
Dominantly Inherited Alzheimer Network (DIAN)
- University of Pittsburgh, Pittsburgh
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT00869817A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
- Pennsylvania Hospital, Philadelphia
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Sep 22, 2026 · NCT07589595A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease
- Flourish Research - Keystone Clinical Studies- Site Number : 8400003, Plymouth Meeting
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Sep 22, 2026 · NCT07688213Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
- Flourish Research ? Philadelphia, Plymouth Meeting
RecruitingPhase 3
Ages 50 to 90 · All sexes · Updated Sep 21, 2026 · NCT07177352PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620
- Perelman Center for Advance Medicine, Philadelphia
RecruitingPhase 3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05456503A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
- Keystone Clinical Studies, Plymouth Meeting
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Sep 17, 2026 · NCT06976203Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders
- Hospital of the University of Pennsylvania, Philadelphia
- Allegheny General Hospital, Pittsburgh
Recruiting
Ages 70 and older · All sexes · Updated Sep 8, 2026 · NCT05929703Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)
- University of Pennsylvania, Philadelphia
RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Sep 4, 2026 · NCT05658913Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
- Thomas Jefferson University - Vickie & Jack Farber Institute for Neuroscience, Philadelphia
RecruitingPhase 2
Ages 55 to 90 · All sexes · Updated Sep 1, 2026 · NCT06808984Biofluid Research on Age-Related or Inherited Neurodegeneration
- University of Pennsylvania, Philadelphia
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07798700A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
- Flourish Research ( Site 1048), Plymouth Meeting
RecruitingPhase 2
Ages 50 to 85 · All sexes · Updated Aug 26, 2026 · NCT07033494Using the EHR to Advance Genomic Medicine Across a Diverse Health System
- Penn Medicine, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT06377033The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study
- University of Pittsburgh, Pittsburgh
Recruiting
Ages 55 to 85 · All sexes · Updated Aug 6, 2026 · NCT05988385Evaluating the Effectiveness of the Health App Recommendation Tool
- University of Pittsburgh, Pittsburgh
RecruitingHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Aug 6, 2026 · NCT07216716Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
- Penn Presbyterian Medical Center, Philadelphia
- University of Pittsburgh Medical Center, Presbyterian Hospital, Pittsburgh
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
- University of Pittsburgh, Pittsburgh
RecruitingPhase 2/3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT06647498A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
- University of Pittsburgh, Pittsburgh
RecruitingPhase 2/3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT05552157Improving Access to Care for Veterans With Memory Loss
- VA Pittsburgh Healthcare System, Pittsburgh
Recruiting
Ages 18 and older · All sexes · Updated Jul 17, 2026 · NCT07117162A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
- Abington Neurological Associates Ltd, Willow Grove
RecruitingPhase 2
Ages 50 to 85 · All sexes · Updated Jun 26, 2026 · NCT07094516Late Onset Alzheimer's Disease
- University of Pittsburgh, Pittsburgh
RecruitingObservational studyHealthy volunteers welcome
Ages 55 and older · All sexes · Updated May 18, 2026 · NCT05010603Trial-Ready Cohort-Down Syndrome (TRC-DS)
- University of Pittsburgh, Co-Enrolling through ABC-DS Only, Pittsburgh
RecruitingObservational study
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109UPenn Observational Research Repository on Neurodegenerative Disease
- University of Pennsylvania, Philadelphia
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT04715399Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183A
- University of Pennsylvania, Philadelphia
RecruitingEarly phase 1
Ages 40 to 85 · All sexes · Updated Dec 23, 2025 · NCT06932809Impact of a Biophoton Therapy on Patients With Brain Disorders
- Tesla MedBed Center, 139 Pittsburgh Road, Butler, PA 16001, Butler
Recruiting
Ages 18 and older · All sexes · Updated Aug 8, 2025 · NCT06147999From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.