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Amyotrophic Lateral Sclerosis clinical trials in Florida

27 studies for Amyotrophic Lateral Sclerosis are looking for participants at sites in Florida.

Cities in Florida

Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS

  • Mayo Clinic, Jacksonville
  • University of South Florida, Tampa
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07322003

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

  • University of South Florida, Department of Psychiatry and Behavioral Neuroscience, Tampa
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034

Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS

  • Mayo Clinic in Florida, Jacksonville
  • University of Miami School of Science, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07287397

Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis

  • Zydus US012, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07023835

Studies in Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Motor Neuron Disorders

  • Mayo Clinic Florida, Jacksonville
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT05474235

PREVENT ALL ALS Study

  • Mayo Clinic, Jacksonville
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06581861

ASSESS ALL ALS Study

  • Nova Southeastern University, Davie
  • Mayo Clinic, Jacksonville
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06578195

Tongue-strengthening Exercises in People With ALS.

  • Nova Southeastern University, Davie
Recruiting
Ages 18 to 99 · All sexes · Updated Aug 12, 2026 · NCT07295990

Study of COYA 302 for the Treatment of ALS

  • Nova Southeastern University, Davie
  • University of Florida Clinical and Translational Research Center, Gainesville
  • University Of Miami, Miami
  • and 1 more
RecruitingPhase 2/3
Ages 18 to 80 · All sexes · Updated Aug 6, 2026 · NCT07161999

Oral Intake of Enteral Nutrition Formula Preceding Placement and Feeding Via GTube and Its Impact on Formula Intolerance in pALS

  • Nova Southeastern University, Cathy J, Husman ALS Center, Fort Lauderdale
Recruiting
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT06609213

Multicenter ALS Imaging Study

  • University of Florida, Gainesville
RecruitingObservational studyMentions payment for participants
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT06735014

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

  • Mayo Clinic Florida, Jacksonville
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04363684

PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS

  • Mayo Clinic Jacksonville, Jacksonville
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Jul 23, 2026 · NCT07142291

Neurologic Stem Cell Treatment Study

  • MD Stem Cells, Coral Springs
Recruiting
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT02795052

Clinical Procedures to Support Research in ALS

  • University of Miami, Miami
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03489278

A Study of Ranolazine in ALS

  • Mayo Clinic Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT06527222

Investigating the Impact of Electrical Stimulation on Facial Pain, Jaw Movement and Oral Health in People With Motor Neuron Disease.

  • Nova Southeastern University, David and Cathy Husman Neuroscience Institute, Davie
Recruiting
Ages 18 and older · All sexes · Updated May 27, 2026 · NCT07187388

ALS/MND Natural History Study Data Repository

  • University of Florida, Gainesville
RecruitingObservational study
Ages 18 to 90 · All sexes · Updated May 20, 2026 · NCT05966038

INdependence Through Endovascular Neuroprosthetic Technology (INTENT): an Early Feasibility Study

  • Mayo Clinic, Jacksonville
Recruiting
Ages 22 and older · All sexes · Updated May 11, 2026 · NCT07543367

AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

  • University of Florida, Gainesville
  • Mayo Clinic in Florida, Jacksonville
  • Orlando Regional Medical Center, Orlando Health Neuroscience Institute, Orlando
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 14, 2026 · NCT06665165

Clinical Research in ALS Study

  • University of Miami, Miami
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT00136500

The Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) Study

  • University of Miami, Miami
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT00317616

Intermuscular Coherence as a Biomarker for ALS

  • University of Miami Miller School of Medicine, Miami
RecruitingObservational studyHealthy volunteers welcome
Ages 20 to 90 · All sexes · Updated Feb 9, 2026 · NCT05104710

Precise Robotically IMplanted Brain-Computer InterfacE

  • University of Miami, Miami
Recruiting
Ages 22 to 75 · All sexes · Updated Jan 9, 2026 · NCT06429735

Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders

  • Mayo Clinic in Florida, Jacksonville
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Dec 16, 2025 · NCT05116943

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

  • Mayo Clinic, Jacksonville
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05137665

Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers

  • Mayo Clinic Jacksonville, Jacksonville
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 to 80 · All sexes · Updated May 2, 2025 · NCT05395624

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.