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Dose Response of Exercise for Arthritis Management

Recruiting

Examination of the Dose Response Relationship Between Physical Activity and Arthritis-Attributable Outcomes

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* 18 years or older
* Have a doctor diagnosed form of arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia
* Ability to read and write in English

Exclusion Criteria:

* Have any contraindications to exercise (besides arthritis)
* Engage in \>45 min/week of Actigraph assessed moderate to vigorous intensity activity
* Are pregnant, breastfeeding, or planning to become pregnant in the next year
* Are planning to relocate out of the Columbia, SC area in the next 12 months,
* Do not have a device compatible with Fitbit
* Have uncontrolled hypertension (e.g., systolic blood pressure \> 160 mmHg or diastolic blood pressure \> 100 mmHg)
* Plan to have a surgery that affects mobility in the next 12 months
* Have a serious cognitive impairment.
* Not willing to be randomized to any of the 3 conditions, do not believe they could adhere to the goals, or do not believe they could achieve the highest dose of activity (150 minutes/week).

About the study

The purpose of the study is to see examine the effects of 3 different levels of physical activity (45 minutes/week, 90 minutes/week, or 150 minutes/week) on arthritis symptoms.

What is being tested

Sponsor: University of South Carolina · Participants: 285 · Started: Mar 28, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06880653

Locations in the U.S.

South CarolinaUniversity of South Carolina, Columbia

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.