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Atherosclerosis clinical trials in Boston, MA

10 studies for Atherosclerosis are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

RecruitingPhase 3
  • Brigham and Women's Hospital Diabetes Program, Boston
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07157774

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

RecruitingPhase 3
  • Brigham and Womens Hospital, Boston
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk

RecruitingPhase 3
  • Massachusetts General Hospital, Boston
Ages 45 to 80 · All sexes · Updated Sep 22, 2026 · NCT07613294

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

RecruitingPhase 2/3
  • Tufts Medical Center, Boston
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05485961

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

RecruitingPhase 3
  • Research Site, Boston
  • Research Site, Boston
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

RecruitingObservational study
  • Massachusetts General Hospital: Rheumatology, Boston
  • Brigham and Womens Hospital, Boston
  • Brigham and Women's Faulkner Hospital, Boston
Ages 35 to 79 · All sexes · Updated Jul 14, 2026 · NCT07315997

Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 30 to 65 · All sexes · Updated Jun 3, 2026 · NCT04496947

Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health

Recruiting
  • Massachusetts General Hospital, Boston
Ages 30 to 75 · All sexes · Updated Mar 23, 2026 · NCT07087431

The Effect of Mindfulness on Vascular Inflammation in Stable Coronary Disease

Recruiting
  • Massachusetts General Hospital, Boston
Ages 45 to 65 · All sexes · Updated Mar 19, 2026 · NCT04505865

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

RecruitingPhase 4
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 18 and older · All sexes · Updated Dec 17, 2025 · NCT02915198

About Atherosclerosis

Atherosclerosis is hardening and narrowing of the arteries caused by the buildup of a fatty substance called plaque. Learn about the risks and prevention.

More about Atherosclerosis on MedlinePlus

Atherosclerosis trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.