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Atrial Fibrillation clinical trials in Cleveland, OH

17 studies for Atrial Fibrillation are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.

The Fourth Left Atrial Appendage Occlusion Study

Recruiting
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05963698

Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic

RecruitingObservational studyHealthy volunteers welcome
  • Cleveland Clinic Foundation, Cleveland
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT00921986

Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation

RecruitingObservational study
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07436299

Evaluation of 4D Intracardiac Echocardiography (ICE) During Structural Heart and Electrophysiology Procedures

Recruiting
  • Cleveland Clinical Foundation, Cleveland
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07806890

Surveillance Trial of the Apple Watch in Reliable Burden Assessment in Unseen Recurrence of Surgically Treated AF

RecruitingObservational study
  • Cleveland Clinic, Cleveland
Ages 22 and older · All sexes · Updated Sep 8, 2026 · NCT07122947

Longitudinal Validation of CIRC Technologies

RecruitingObservational studyHealthy volunteers welcome
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07081711

Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)

Recruiting
  • Cleveland Clinic Foundation, Cleveland
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07298473

Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

Recruiting
  • Cleveland Clinic, Cleveland
Ages 18 to 80 · All sexes · Updated Jul 15, 2026 · NCT06784466

Tracking Results of Ablations to Combat AF Registry Generation 2

RecruitingObservational study
  • UH Cleveland Harrington Heart & Vascular Institute, Cleveland
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05111015

BoxX-NoAF Clinical Trial

RecruitingHealthy volunteers welcome
  • Cleveland Clinic Foundation, Cleveland
Ages 65 and older · All sexes · Updated Jun 29, 2026 · NCT06989775

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

RecruitingPhase 3
  • Cleveland Clinic Foundation, Cleveland
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT04045665

Development of CIRC Technologies

RecruitingObservational studyHealthy volunteers welcome
  • Cardiovascular Innovation Research Center, Cleveland
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT05654272

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

RecruitingPhase 3
  • UH Cleveland Medical Center, Cleveland
  • MetroHealth Medical Center, Cleveland
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT03907046

Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):

Recruiting
  • Cleveland Clinic, Cleveland
Ages 18 to 85 · All sexes · Updated Apr 13, 2026 · NCT07087587

TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation

RecruitingPhase 2
  • Cleveland Clinic, Cleveland
Ages 18 to 80 · All sexes · Updated Jan 13, 2026 · NCT06802081

Intracardiac Echocardiography Guided Watchman Device Implant

Recruiting
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Oct 21, 2025 · NCT06007872

Low Voltage-Directed Catheter Ablation for Atrial Fibrillation

Recruiting
  • MetroHealth Medical Center, Cleveland
Ages 18 to 85 · All sexes · Updated Jun 10, 2024 · NCT03355456

About Atrial Fibrillation

Atrial fibrillation (AF or AFib) is the most common type of arrhythmia (irregular heartbeat). Read about symptoms and treatment.

More about Atrial Fibrillation on MedlinePlus

Atrial Fibrillation trials in other cities

Other studies in Cleveland

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.