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Bladder Cancer clinical trials in Illinois

30 studies for Bladder Cancer are looking for participants at sites in Illinois.

Cities in Illinois

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

  • Rush MD Anderson Cancer Center, Chicago
  • University of Chicago Comprehensive Cancer Center, Chicago
  • Carle at The Riverfront, Danville
  • and 12 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT03866382

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

  • Rush-Copley Medical Center, Aurora
  • OSF Saint Joseph Medical Center, Bloomington
  • Illinois CancerCare-Bloomington, Bloomington
  • and 38 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07061964

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

  • Associated Urological Specialists - Chicago Ridge ( Site 0139), Chicago Ridge
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06833073

Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

  • Memorial Hospital, Shiloh
  • Siteman Cancer Center - Shiloh, Shiloh
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07421700

A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

  • Northwestern Memorial Hospital, Chicago
  • Northwestern University - Feinberg School of Medicine, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07206225

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

  • City of Hope Cancer Center-Chicago, Zion
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

  • Rush MD Anderson Cancer Center, Chicago
  • Carle at The Riverfront, Danville
  • Cancer Care Specialists of Illinois - Decatur, Decatur
  • and 11 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06770582

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • University of Illinois Cancer Center, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06172478

DESTINY-PANTUMOUR04

  • Research Site, Decatur
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

  • University of Illinois at Chicago, Chicago
  • University of Chicago Medical Center, Chicago
  • Endeavor Health, Evanston
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

  • Illinois Cancer Specialists, Niles
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07566156

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

  • University of Chicago Hospital, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06465069

Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

  • Associated Urological Specialists, Chicago Ridge
  • Uropartners, Glenview
  • Accellacare, Lisle
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06567743

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • OSF Saint Anthony's Health Center, Alton
  • Rush-Copley Medical Center, Aurora
  • Advocate Outpatient Center - Aurora, Aurora
  • and 54 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)

  • University of Chicago Medical Center ( Site 5037), Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07232602

Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

  • Comprehensive Urologic Care, Lake Barrington
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT05951179

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

  • Research Site, Niles
  • Research Site, Peoria
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT07129993

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

  • The University of Chicago Medical Center (UCMC), Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05614739

Measuring Surgical Recovery After Radical Cystectomy

  • University of Chicago, Chicago
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT03193970

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

  • OSF Saint Anthony's Health Center, Alton
  • OSF Saint Joseph Medical Center, Bloomington
  • Illinois CancerCare-Bloomington, Bloomington
  • and 32 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07097142

Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

  • Northwestern University, Chicago
  • University of Illinois, Chicago
  • Loyola University Medical Center, Maywood
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07000084

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

  • UChicago Medicine - River East, Chicago
  • University of Chicago Medical Center, Chicago
  • Accellacare - Deerfield, Deerfield
  • and 5 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT04879329

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

  • Ingalls Family Care Center, Calumet City
  • UChicago Medicine - River East, Chicago
  • The University Of Chicago, Chicago
  • and 13 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Integrated Cancer Repository for Cancer Research

  • Rush-Copley Cancer Care Center, Aurora
  • Rush-Copley Healthcare Center, Yorkville
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Pemetrexed Response in Relation to Tumor Alterations of Gene Status for the Treatment of Patients With Metastatic Urothelial Bladder Cancer and Other Solid Tumors

  • Northwestern University, Chicago
  • Northwestern Medicine Orland Park, Orland Park
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06630416

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

  • The University of Chicago Comprehensive Cancer Center, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

Blue Light Cystoscopy With Cysview® Registry

  • Northwestern University, Chicago
  • Northshore University Health System, Evanston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 18, 2025 · NCT02660645

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Chicago
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Prospective Validation Study of High Volume Urine DNA Testing in Individuals With Suspicion of Urothelial Cancer

  • Jesse Brown Department Of Veterans Affairs Medical Center, Chicago
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Oct 10, 2025 · NCT06310759

Comprehensive Geriatric Assessment (Tests) for Bladder Cancer Participants Undergoing Radical Cystectomy

  • University of Chicago Medicine Comprehensive Cancer Center, Chicago
Recruiting
Ages 65 and older · All sexes · Updated Oct 3, 2025 · NCT06427824

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.