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Bladder Cancer clinical trials in Springfield, IL

6 studies for Bladder Cancer are looking for participants at sites in and around Springfield (within about 30 miles). Open a study to see who can join and how to contact the study team.

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT03866382

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

RecruitingPhase 2
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07061964

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

RecruitingPhase 2
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06770582

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

RecruitingPhase 3
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07097142

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • Southern Illinois University - Simmons Cancer Institute, Springfield
  • Springfield Clinic Radiology - 800 Building, Springfield
  • Springfield Clinic Urgent Care Plus, Springfield
  • and 4 more
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

About Bladder Cancer

Bladder cancer symptoms range from lower back pain to blood in your urine. Read about important risk factors and find a list of treatments available

More about Bladder Cancer on MedlinePlus

Bladder Cancer trials in other cities

Other studies in Springfield

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.