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Breast Cancer clinical trials in Naperville, IL

10 studies for Breast Cancer are looking for participants at sites in and around Naperville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With Early-stage and Advanced HR+ Breast Cancer

RecruitingPhase 1
  • Duly Health and Care, Lisle · 4 mi away
Ages 18 to 55 · Women · Updated Nov 12, 2026 · NCT07310420

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Accellacare of Duly, Lisle · 4 mi away
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07174336

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Edward Hospital/Cancer Center, Naperville
  • Northwestern Medicine Cancer Center Warrenville, Warrenville · 3 mi away
  • Rush MD Anderson Cancer Center at Rush Lisle, Lisle · 4 mi away
  • and 1 more
Ages 18 to 50 · All sexes · Updated Nov 4, 2026 · NCT06748222

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Advocate Good Samaritan Hospital, Downers Grove · 7 mi away
Ages 40 to 75 · All sexes · Updated Nov 4, 2026 · NCT05334069

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Advocate Good Samaritan Hospital, Downers Grove · 7 mi away
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06418204

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3
  • Edward Hospital/Cancer Center, Naperville
  • Northwestern Medicine Cancer Center Warrenville, Warrenville · 3 mi away
  • Rush MD Anderson Cancer Center at Rush Lisle, Lisle · 4 mi away
  • and 1 more
Ages 18 to 60 · Women · Updated Nov 4, 2026 · NCT05879926

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

RecruitingPhase 3
  • Endeavor Health Cancer Institute at Swedish Hospital, Naperville
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT07062965

Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

RecruitingPhase 2
  • Northwestern Medicine Chicago Proton Center, Warrenville · 3 mi away
Ages 50 and older · Women · Updated Sep 29, 2026 · NCT01766297

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

RecruitingPhase 3
  • Northwestern Medicine Cancer Center Warrenville, Warrenville · 3 mi away
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • Edward Hospital/Cancer Center, Naperville
  • Northwestern Medicine Cancer Center Warrenville, Warrenville · 3 mi away
  • Advocate Good Samaritan Hospital, Downers Grove · 7 mi away
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. Learn about the types, diagnosis, and treatments.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Naperville

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.