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Heart Failure clinical trials in Naperville, IL

13 studies for Heart Failure are looking for participants at sites in and around Naperville (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

RecruitingPhase 3
  • Research Site, Winfield · 5 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

RecruitingPhase 3
  • Midwest Cardiovascular Institute, Naperville
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574

Alleviant ALLAY-HFrEF Study

Recruiting
  • Midwest Cardiovascular Institute, Naperville
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06812533

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

RecruitingPhase 3
  • Research Site, Winfield · 5 mi away
Ages 18 to 130 · All sexes · Updated Sep 11, 2026 · NCT06307652

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

RecruitingPhase 3
  • Naperville, IL Investigative Site 10025, Naperville
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

RecruitingPhase 3
  • CON-10025, Naperville, IL, Naperville
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

Recruiting
  • Midwest Cardiovascular Institute, Naperville
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07069738

Alleviant ALLAY-HF Study

Recruiting
  • Midwest Cardiovascular Institute, Naperville
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • Advocate Health System, Downers Grove · 7 mi away
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • Advocate Health & Hospitals Corporation, Oakbrook Terrace · 10 mi away
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Midwest Cardiovascular Institute (MCI), Naperville
  • Advocate Good Samaritan, Downers Grove · 7 mi away
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart Failure

RecruitingObservational study
  • Endotronix, Naperville
Ages 18 and older · All sexes · Updated Nov 19, 2025 · NCT06783335

AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

RecruitingObservational study
  • Midwest Cardiovascular Center, Naperville
  • Advocate Illinois Masonic Health Center, Downers Grove · 7 mi away
Ages 22 and older · All sexes · Updated Mar 26, 2025 · NCT06378632

About Heart Failure

Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.

More about Heart Failure on MedlinePlus

Heart Failure trials in other cities

Other studies in Naperville

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.