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Breast Cancer clinical trials in Arlington, VA

46 studies for Breast Cancer are looking for participants at sites in and around Arlington (within about 30 miles). Open a study to see who can join and how to contact the study team.

Study of AVZO-021 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05867251

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

RecruitingPhase 2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07007559

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

Recruiting
  • Inova, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07214532

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer

RecruitingPhase 2
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
Ages 18 and older · Women · Updated Sep 22, 2026 · NCT07287098

A Study of JNJ-101684362 (HLD-0117) in Patients With Metastatic Breast Cancer

RecruitingPhase 1
  • Next Virginia, Fairfax · 11 mi away
Ages 18 and older · Women · Updated Sep 21, 2026 · NCT07524855

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

RecruitingPhase 1/2
  • NEXT Oncology, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07109726

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

RecruitingPhase 1/2
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
  • Virginia Cancer Specialists, PC, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06324357

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

RecruitingPhase 3
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • NEXT Oncology - Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

RecruitingPhase 1/2
  • Next Oncology, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT05315700

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

RecruitingPhase 1/2
  • Virginia Cancer Specialists-Fairfax, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07287917

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

RecruitingPhase 3
  • Virginia Cancer Specialists, PC, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06982521

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3
  • Kaiser Permanente Tysons Corner Medical Center, McLean · 5 mi away
  • Kaiser Permanente-Burke Medical Center, Burke · 11 mi away
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
  • Inova Fair Oaks Hospital, Fairfax · 11 mi away
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

A Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors

RecruitingPhase 1/2
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07287995

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07029399

A Study of Mutant Selective-Inhibitor (CGT6297), in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07383506

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

RecruitingPhase 2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07102381

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

RecruitingPhase 1
  • Inova Schar Cancer Institute, Falls Church · 4 mi away
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06774963

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

RecruitingPhase 3
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
  • Inova Fair Oaks Hospital, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

RecruitingPhase 3
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 to 100 · All sexes · Updated Aug 6, 2026 · NCT05232916

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • USOR Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Inova Fairfax Hospital, Falls Church · 4 mi away
  • Kaiser Permanente Tysons Corner Medical Center, McLean · 5 mi away
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
  • and 1 more
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07524322

Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy

RecruitingPhase 3
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
Ages 19 and older · Women · Updated Jul 10, 2026 · NCT05856773

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • USO-Virginia Cancer Specialists, PC, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

Pre-Operative Window of ET to Inform RT Decisions (POWER II)

RecruitingPhase 3
  • INOVA Schar Cancer, Fairfax · 11 mi away
Ages 65 and older · Women · Updated Jun 30, 2026 · NCT06507618

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

RecruitingPhase 1/2
  • NEXT Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05377996

Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • NEXT, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT06993844

Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · Women · Updated Jun 22, 2026 · NCT05573126

Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)

RecruitingPhase 1/2
  • Inova Schar Cancer Institute ( Site 0051), Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06686394

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

RecruitingPhase 3
  • Virginia Cancer Specialists, PC, Reston · 14 mi away
  • Virginia Cancer Specialists, Manassas · 22 mi away
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07062965

A Study to Evaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast Cancer

RecruitingPhase 1
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · Women · Updated Apr 22, 2026 · NCT05683418

Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • NEXT Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT07424547

A Study of DB-1310 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Apr 6, 2026 · NCT05785741

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

RecruitingPhase 1/2
  • NEXT, Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT07145255

Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

RecruitingPhase 2
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
Ages 50 and older · Women · Updated Sep 9, 2025 · NCT01766297

Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BTX-9341 in Advanced and/or Metastatic Breast Cancer

RecruitingPhase 1
  • Biotheryx Investigative Site, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 6, 2025 · NCT06515470

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Arlington

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.