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Breast Cancer clinical trials in Arlington, VA

50 studies for Breast Cancer are looking for participants at sites in and around Arlington (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Phase 1/1b Study of PRT13722 in Participants With Advanced HR+/HER2- Breast Cancer

RecruitingPhase 1

NEXT Virginia, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07905001

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

RecruitingPhase 2

Virginia Cancer Specialists, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07007559

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome

Inova Schar Cancer Institute, Fairfax · 11 mi away
Inova Fair Oaks Hospital, Fairfax · 11 mi away

Ages 45 to 75 · All sexes · Updated Nov 6, 2026 · NCT06995898

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

RecruitingPhase 1

NEXT Virginia, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07029399

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

RecruitingPhase 1/2

Inova Schar Cancer Institute, Fairfax · 11 mi away
Virginia Cancer Specialists, PC, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06324357

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

Recruiting

Inova, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07214532

Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

RecruitingPhase 1/2

Next Oncology, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT05315700

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

RecruitingPhase 3

Virginia Cancer Specialists, PC, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06982521

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3

Virginia Cancer Specialists, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07174336

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3

Inova Fairfax Hospital, Falls Church · 4 mi away
Kaiser Permanente Tysons Corner Medical Center, McLean · 5 mi away
Inova Schar Cancer Institute, Fairfax · 11 mi away
and 1 more

Ages 18 to 50 · All sexes · Updated Nov 4, 2026 · NCT06748222

A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer

RecruitingPhase 2

Inova Schar Cancer Institute, Fairfax · 11 mi away

Ages 18 and older · Women · Updated Nov 4, 2026 · NCT07287098

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2

USOR Virginia Cancer Specialists, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT05579366

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

RecruitingPhase 1

Inova Schar Cancer Institute, Falls Church · 4 mi away

Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06400472

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3

Kaiser Permanente Tysons Corner Medical Center, McLean · 5 mi away
Kaiser Permanente-Burke Medical Center, Burke · 11 mi away

Ages 18 to 60 · Women · Updated Nov 4, 2026 · NCT05879926

A Study of JNJ-101684362 (HLD-0117) in Patients With Metastatic Breast Cancer

RecruitingPhase 1

Next Virginia, Fairfax · 11 mi away

Ages 18 and older · Women · Updated Nov 3, 2026 · NCT07524855

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

RecruitingPhase 1

NEXT Virginia, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT07524322

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

RecruitingPhase 1

Inova Schar Cancer Institute, Falls Church · 4 mi away

Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06774963

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

RecruitingPhase 2

Virginia Cancer Specialists, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT07102381

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

RecruitingPhase 1/2

NEXT Oncology, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07109726

Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic

RecruitingPhase 1

NEXT Oncology Virginia, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT07807345

A Study of Mutant Selective-Inhibitor (CGT6297), in Patients With Advanced Solid Tumors

RecruitingPhase 1

NEXT Virginia, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT07383506

A Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors

RecruitingPhase 1/2

NEXT Virginia, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT07287995

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

RecruitingPhase 1/2

Virginia Cancer Specialists-Fairfax, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT07287917

Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)

RecruitingPhase 1/2

Inova Schar Cancer Institute ( Site 0051), Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT06686394

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

RecruitingPhase 3

Virginia Cancer Specialists, PC, Arlington
Virginia Cancer Specialists, Fairfax · 11 mi away
Virginia Cancer Specialists, PC, Reston · 14 mi away
and 1 more

Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT07062965

A Study to Evaluate ATX-898 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2

NEXT Virginia Cancer Center- Merrifield Tech Center, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07767474

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1

Virginia Cancer Specialists, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06293898

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

RecruitingPhase 3

Inova Schar Cancer Institute ( Site 0025), Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06312176

Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2

NEXT, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06993844

A Study of PHST001 in Advanced Solid Tumors

RecruitingPhase 1

NEXT Oncology - Virginia, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06840886

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2

Virginia Cancer Specialists, Fairfax · 11 mi away

Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

RecruitingPhase 2

Inova Schar Cancer Institute, Fairfax · 11 mi away

Ages 50 and older · Women · Updated Sep 29, 2026 · NCT01766297

Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy

RecruitingPhase 3

Inova Schar Cancer Institute, Fairfax · 11 mi away

Ages 19 and older · Women · Updated Sep 29, 2026 · NCT05856773

Study of AVZO-021 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2

Avenzo Therapeutics Recruiting Site, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05867251

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

RecruitingPhase 3

Research Site, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06103864

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

RecruitingPhase 1

NEXT Oncology, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1

NEXT Oncology - Virginia Cancer Specialists, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

RecruitingPhase 3

Inova Schar Cancer Institute, Fairfax · 11 mi away
Inova Fair Oaks Hospital, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

RecruitingPhase 3

Virginia Cancer Specialists, Fairfax · 11 mi away

Ages 18 to 100 · All sexes · Updated Aug 6, 2026 · NCT05232916

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2

USO-Virginia Cancer Specialists, PC, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

Pre-Operative Window of ET to Inform RT Decisions (POWER II)

RecruitingPhase 3

INOVA Schar Cancer, Fairfax · 11 mi away

Ages 65 and older · Women · Updated Jun 30, 2026 · NCT06507618

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

RecruitingPhase 1/2

NEXT Oncology Virginia, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05377996

Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

RecruitingPhase 1/2

Virginia Cancer Specialists, Fairfax · 11 mi away

Ages 18 and older · Women · Updated Jun 22, 2026 · NCT05573126

A Study to Evaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast Cancer

RecruitingPhase 1

Virginia Cancer Specialists, Fairfax · 11 mi away

Ages 18 and older · Women · Updated Apr 22, 2026 · NCT05683418

Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors

RecruitingPhase 1

NEXT Oncology Virginia, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT07424547

A Study of DB-1310 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2

NEXT Virginia, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Apr 6, 2026 · NCT05785741

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

RecruitingPhase 1/2

Virginia Cancer Specialists, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

RecruitingPhase 1/2

NEXT, Virginia, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT07145255

First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

RecruitingPhase 1

Inova Schar Cancer Center, Fairfax · 11 mi away
NEXT Virginia, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Sep 22, 2025 · NCT05216432

Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BTX-9341 in Advanced and/or Metastatic Breast Cancer

RecruitingPhase 1

Biotheryx Investigative Site, Fairfax · 11 mi away

Ages 18 and older · All sexes · Updated Jun 6, 2025 · NCT06515470

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. Learn about the types, diagnosis, and treatments.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Arlington

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.