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Colorectal Cancer clinical trials in Arlington, VA

52 studies for Colorectal Cancer are looking for participants at sites in and around Arlington (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

RecruitingPhase 1/2
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
  • Virginia Cancer Specialists, PC, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06324357

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

RecruitingPhase 1
  • ALX Center 2, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

RecruitingPhase 2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07659795

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Virginia Cancer Specialists, PC, Arlington
  • Virginia Cancer Specialists, PC, Fairfax · 11 mi away
  • Virginia Cancer Specialists, PC, Reston · 14 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

RecruitingPhase 3
  • Virginia Cancer Specialists, Arlington
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06750094

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

RecruitingPhase 3
  • Virginia Cancer Specialists, Arlington
  • Inova Schar Cancer Institute Dept of Fairfax Hospital, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06662786

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • NEXT Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • Next Oncology Virginia Cancer Specialist, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

RecruitingPhase 1
  • NEXT - Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07349537

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Clinical Study Site, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
  • Inova Fair Oaks Hospital, Fairfax · 11 mi away
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 to 99 · All sexes · Updated Sep 1, 2026 · NCT06983743

A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer

RecruitingPhase 2
  • Inova Schar Cancer, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT06992258

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07227168

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT07066657

A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Clinical Trial Site, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07749586

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

RecruitingPhase 1/2
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT07397338

AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Next Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07094113

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

RecruitingPhase 2
  • Inova Schar Cancer Institute - Fairfax - Innovation Park Drive /ID# 274586, Fairfax · 11 mi away
  • Virginia Cancer Specialists - Fairfax /ID# 274339, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT07023289

A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT07300150

A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors

RecruitingPhase 1/2
  • NEXT Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT07169734

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

RecruitingPhase 1
  • NEXT Texas LLC - Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT07503808

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 to 99 · All sexes · Updated Jun 16, 2026 · NCT07540572

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

RecruitingPhase 1
  • Research Site, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • NEXT Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors

RecruitingPhase 1
  • NEXT Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT07454642

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

RecruitingPhase 1/2
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated May 28, 2026 · NCT07223047

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

RecruitingPhase 1
  • NEXT Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT07094204

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Next Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

A Study of TSN1611 Treating Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

RecruitingPhase 1/2
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 to 75 · All sexes · Updated Apr 24, 2026 · NCT06385925

A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

RecruitingPhase 1
  • NEXT Virginia, LLC, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT06720987

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

RecruitingPhase 1/2
  • NEXT, Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT07145255

A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT07317505

Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

RecruitingPhase 1
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Dec 17, 2025 · NCT05856981

A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • Next Oncology, Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jan 26, 2024 · NCT05746897

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Arlington

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.