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Cardiovascular Disease clinical trials in Ohio

37 studies for Cardiovascular Disease are looking for participants at sites in Ohio.

Cities in Ohio

Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)

  • The Ohio State University Wexner Medical Center, Columbus
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 29, 2026 · NCT07585968

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

  • Aultman Hospital, Canton
  • Heart House Research Foundation LLC, Springfield
  • ProMedica Toledo Hospital, Toledo
  • and 1 more
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06909565

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

  • Velocity Clinical Research, Cincinnati, Springdale, Cincinnati
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07783802

Product Surveillance Registry

  • Cleveland
  • Columbus
  • Dayton
  • and 1 more
RecruitingObservational study
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

  • Clinical Trial Site, Beavercreek
  • Clinical Trial Site, Cincinnati
  • Clinical Trial Site, Cincinnati
  • and 7 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109

Zenith® Fenestrated+ Clinical Study

  • Cleveland Clinic Foundation, Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

  • The Christ Hospital, Cincinnati
  • Velocity Clinical Research-Cincinnati-69044, Cincinnati
  • Centricity Research-Columbus-68879, Columbus
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07064473

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

  • The Christ Hospital, Cincinnati
  • University Hospitals Cleveland Medical Center, Cleveland
  • The Ohio State University Wexner Medical Center, Columbus
  • and 1 more
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

  • The Christ Hospital - Cincinnati, Cincinnati
  • Cleveland Clinic, Cleveland
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

  • Akron Hospital Summa Health System, Akron
  • Aultman Hospital, Canton
  • Cleveland Clinic Foundation, Cleveland
  • and 1 more
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

  • Cleveland Clinic Foundation, Cleveland
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

  • Cincinnati VA Medical Center, Cincinnati
  • Case Western Reserve University, Cleveland
  • Ohio State University, Columbus
  • and 1 more
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

  • Cincinnati Children's Hospital Medical Center, Cincinnati
  • Nationwide Children's Hospital, Columbus
RecruitingObservational study
Ages 7 and older · All sexes · Updated Aug 25, 2026 · NCT05705531

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

  • Research Site, Cincinnati
  • Research Site, Columbus
  • Research Site, Lima
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

  • Aultman Cardiology Clinical Trials, Canton
  • The Christ Hospital, Cincinnati
  • Velocity Clinical Research - Cincinnati, Cincinnati
  • and 2 more
RecruitingPhase 3
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

ELEVATE-HFpEF Clinical Study

  • The Ohio State University Wexner Medical Center, Columbus
  • Mount Carmel East, Columbus
Recruiting
Ages 40 and older · All sexes · Updated Aug 3, 2026 · NCT06678841

The Oxford Risk Factors And Non-Invasive Imaging Study

  • Cleveland Clinic, Cleveland
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Jul 31, 2026 · NCT05169333

Longitudinal Validation of CIRC Technologies

  • Cleveland Clinic, Cleveland
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07081711

The TRICURE EFS Study

  • The Christ Hospital, Cincinnati
Recruiting
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06506942

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

  • The Christ Hospital- Cincinnati, Cincinnati
  • University of Cincinnati, Cincinnati
  • University Hospital (Cleveland), Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Cardiovascular and Metabolic Sciences Biorepository

  • Cleveland Clinic Main Campus, Cleveland
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06560424

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

  • Christ Hospital, Cincinnati
  • The Cleveland Clinic Foundation, Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

Development of CIRC Technologies

  • Cardiovascular Innovation Research Center, Cleveland
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT05654272

CV Imaging of Metabolic Interventions

  • Cardiovascular Innovation Research Center, Cleveland
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT05650307

Pivotal Study for the Cardiac Performance System (CPS)

  • The Ohio State University Medical Center, Columbus
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT06870591

Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients

  • LifeCare Alliance, Columbus
Recruiting
Ages 60 and older · All sexes · Updated Apr 13, 2026 · NCT06586970

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

  • Lindner Research Center at the Christ Hospital, Cincinnati
  • Cleveland Clinic, Cleveland
  • The Ohio State University, Columbus
  • and 1 more
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Heart Institute BioRepository (HIBR) for Pediatric Heart Disease

  • Children's Hospital Medical Center, Cincinnati, Cincinnati
RecruitingObservational study
All ages · All sexes · Updated Apr 8, 2026 · NCT07478354

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

  • Cleveland Clinic Foundation, Cleveland
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Mar 24, 2026 · NCT06217302

Vascular Lab Resource (VLR) Biorepository

  • Cleveland Clinic, Cleveland
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 19, 2025 · NCT05628948

Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention

  • The Ohio State University, Columbus
Recruiting
Ages 18 and older · Men · Updated Oct 6, 2025 · NCT06055036

MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

  • University Hospitals, Cleveland Medical Center, Cleveland
  • Cleveland Clinic, Cleveland
Recruiting
Ages 18 to 80 · All sexes · Updated Sep 11, 2025 · NCT06271590

Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

  • Nationwide Children's Hospital, Columbus
RecruitingPhase 2
All ages · All sexes · Updated Jun 27, 2025 · NCT04467671

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

  • Cleveland Clinic, Cleveland
Recruiting
Ages 18 to 110 · All sexes · Updated Feb 25, 2025 · NCT05908331

PARTNER 3 Trial - Aortic Valve-in-Valve

  • The Christ Hospital, Cincinnati
  • The Cleveland Clinic Foundation, Cleveland
Recruiting
All ages · All sexes · Updated May 10, 2024 · NCT03003299

Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"

  • Cleveland Clinic, Cleveland
Recruiting
Ages 40 and older · All sexes · Updated Aug 4, 2023 · NCT05919342

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.