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Cardiovascular Disease clinical trials in Ohio
35 studies for Cardiovascular Disease are looking for participants at sites in Ohio.
Cities in Ohio
- Cleveland20 studies
- Cincinnati16 studies
- Columbus13 studies
- Dayton5 studies
- Toledo3 studies
- Lima3 studies
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
- Clinical Trial Site, Beavercreek
- Clinical Trial Site, Cincinnati
- Clinical Trial Site, Cincinnati
- and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07181109EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
- The Christ Hospital, Cincinnati
- Velocity Clinical Research-Cincinnati-69044, Cincinnati
- Centricity Research-Columbus-68879, Columbus
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07064473VDyne TriNova Transcatheter Tricuspid Valve Replacement Study to Evaluate Safety and Clinical Efficacy in Patients With Symptomatic Severe Tricuspid Valve Regurgitation (TRIVITA Pivotal Trial)
- The Christ Hospital, Cincinnati
Recruiting
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07516444A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
- Cleveland Clinic, Cleveland
Recruiting
Ages 18 to 85 · All sexes · Updated Nov 10, 2026 · NCT07214376Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts
- Nationwide Children's Hospital, Columbus
RecruitingPhase 2
All ages · All sexes · Updated Nov 10, 2026 · NCT04467671Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Christ Hospital, Cincinnati
- The Cleveland Clinic Foundation, Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06526195A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
- Velocity Clinical Research, Cincinnati, Springdale, Cincinnati
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07783802ELEVATE-HFpEF Clinical Study
- The Ohio State University Wexner Medical Center, Columbus
- Mount Carmel East, Columbus
Recruiting
Ages 40 and older · All sexes · Updated Nov 3, 2026 · NCT06678841Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
- The Christ Hospital, Cincinnati
- University Hospitals Cleveland Medical Center, Cleveland
- The Ohio State University Wexner Medical Center, Columbus
- and 1 more
Recruiting
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT03242642Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
- Aultman Hospital, Canton
- Heart House Research Foundation LLC, Springfield
- ProMedica Toledo Hospital, Toledo
- and 1 more
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06909565The TRICURE EFS Study
- The Christ Hospital, Cincinnati
Recruiting
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06506942Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)
- The Ohio State University Wexner Medical Center, Columbus
Recruiting
Ages 18 to 85 · All sexes · Updated Oct 26, 2026 · NCT07585968Product Surveillance Registry
- Cleveland
- Columbus
- Dayton
- and 1 more
RecruitingObservational study
All ages · All sexes · Updated Oct 20, 2026 · NCT01524276Zenith® Fenestrated+ Clinical Study
- Cleveland Clinic Foundation, Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT04875429Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)
- Cleveland Clinic Foundation, Cleveland
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
- Cincinnati VA Medical Center, Cincinnati
- Case Western Reserve University, Cleveland
- Ohio State University, Columbus
- and 1 more
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma
- Cincinnati Children's Hospital Medical Center, Cincinnati
- Nationwide Children's Hospital, Columbus
RecruitingObservational study
Ages 7 and older · All sexes · Updated Aug 25, 2026 · NCT05705531A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
- Research Site, Cincinnati
- Research Site, Columbus
- Research Site, Lima
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
- Aultman Cardiology Clinical Trials, Canton
- The Christ Hospital, Cincinnati
- Velocity Clinical Research - Cincinnati, Cincinnati
- and 2 more
RecruitingPhase 3
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012The Oxford Risk Factors And Non-Invasive Imaging Study
- Cleveland Clinic, Cleveland
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Jul 31, 2026 · NCT05169333Longitudinal Validation of CIRC Technologies
- Cleveland Clinic, Cleveland
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07081711PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- The Christ Hospital- Cincinnati, Cincinnati
- University of Cincinnati, Cincinnati
- University Hospital (Cleveland), Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487Cardiovascular and Metabolic Sciences Biorepository
- Cleveland Clinic Main Campus, Cleveland
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06560424CV Imaging of Metabolic Interventions
- Cardiovascular Innovation Research Center, Cleveland
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT05650307Development of CIRC Technologies
- Cardiovascular Innovation Research Center, Cleveland
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT05654272Pivotal Study for the Cardiac Performance System (CPS)
- The Ohio State University Medical Center, Columbus
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT06870591Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients
- LifeCare Alliance, Columbus
Recruiting
Ages 60 and older · All sexes · Updated Apr 13, 2026 · NCT06586970The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
- Lindner Research Center at the Christ Hospital, Cincinnati
- Cleveland Clinic, Cleveland
- The Ohio State University, Columbus
- and 1 more
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152Heart Institute BioRepository (HIBR) for Pediatric Heart Disease
- Children's Hospital Medical Center, Cincinnati, Cincinnati
RecruitingObservational study
All ages · All sexes · Updated Apr 8, 2026 · NCT07478354Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
- Cleveland Clinic Foundation, Cleveland
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Mar 24, 2026 · NCT06217302Vascular Lab Resource (VLR) Biorepository
- Cleveland Clinic, Cleveland
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 19, 2025 · NCT05628948MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels
- University Hospitals, Cleveland Medical Center, Cleveland
- Cleveland Clinic, Cleveland
Recruiting
Ages 18 to 80 · All sexes · Updated Sep 11, 2025 · NCT06271590MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
- Cleveland Clinic, Cleveland
Recruiting
Ages 18 to 110 · All sexes · Updated Feb 25, 2025 · NCT05908331PARTNER 3 Trial - Aortic Valve-in-Valve
- The Christ Hospital, Cincinnati
- The Cleveland Clinic Foundation, Cleveland
Recruiting
All ages · All sexes · Updated May 10, 2024 · NCT03003299Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"
- Cleveland Clinic, Cleveland
Recruiting
Ages 40 and older · All sexes · Updated Aug 4, 2023 · NCT05919342From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.