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Colon Cancer clinical trials in Florida

29 studies for Colon Cancer are looking for participants at sites in Florida.

Cities in Florida

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

  • Florida Cancer Specialists - South ( Site 7002), Fort Myers
  • Mayo Clinic in Florida ( Site 0092), Jacksonville
  • Orlando Health Cancer Institute ( Site 0065), Orlando
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06997497

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

  • Florida Cancer Specialists, Bonita Springs
  • Florida Cancer Specialists, Bradenton
  • Comprehensive Hematology Oncology, Brandon
  • and 19 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • Florida Cancer Specialists, Sarasota
  • Moffitt Cancer Center and Research Institute, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

  • Florida Cancer Specialists & Research Institute - Sarasota, Sarasota
  • Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

  • Florida Oncology & Hematology, Fort Myers
  • University of Florida Health, Gainesville
  • Sylvester Comprehensive Cancer Center, Miami
  • and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • Memorial Healthcare System, Hollywood
  • The Oncology Institute of Hope & Innovation, Lakeland
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

  • Holy Cross Hospital, Fort Lauderdale
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07283939

Family Communications After Genetic Testing

  • Holy Cross Hospital, Fort Lauderdale
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07143487

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

  • AdventHealth Altamonte, Altamonte Springs
  • AdventHealth Celebration, Celebration
  • Morton Plant Hospital, Clearwater
  • and 21 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05174169

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • Bay Pines VA Healthcare System, Bay Pines
  • Malcom Randall Veterans Administration Medical Center, Gainesville
  • and 8 more
Recruiting
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673

Shield Post-Approval Study Protocol

  • Gastroenterology Consultants of Boca Raton, LLC, Boca Raton
  • Manuel Espinel MD PA, Delray Beach
  • Innova Pharma Research, LLC, Doral
  • and 5 more
RecruitingObservational studyHealthy volunteers welcome
Ages 45 to 81 · All sexes · Updated Aug 7, 2026 · NCT06880055

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

  • Xencor Investigative Site, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

  • Florida Cancer Specialists, Sarasota
  • Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

Integrated Cancer Repository for Cancer Research

  • Florida Hospital Memorial Medical Center, Daytona Beach
  • Florida Hospital DeLand, DeLand
  • Florida Hospital FISH, Orange City
  • and 2 more
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Utero-ovarian Transposition in Patients With Pelvic Malignancies Undergoing Whole Pelvic Radiotherapy

  • Tampa General Hospital, Tampa
Recruiting
18 Months – 40 Months · Women · Updated Jun 24, 2026 · NCT07419490

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

  • Mayo Clinic, Jacksonville
  • Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

  • Research Site, Orlando
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

  • Florida Cancer Specialists, Sarasota
  • Lee Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

  • Memorial Healthcare System, Hollywood
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

  • Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

  • ALX Center 7, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated May 12, 2026 · NCT07085091

A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials

  • University of Florida, Gainesville
  • Mayo Clinic in Florida, Jacksonville
  • University of Miami, Miami
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated May 8, 2026 · NCT05655494

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

  • Sylvester Comprehensive Cancer Center - University of Miami Health System, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer

  • AdventHealth, Orlando
Recruiting
Ages 18 and older · All sexes · Updated Jan 7, 2026 · NCT05773144

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Jacksonville
  • Massive Bio SYNERGY-AI site, Miami
  • Massive Bio SYNERGY-AI site, Tampa
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

  • Mayo Clinic, Jacksonville
  • Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT06682793

Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer

  • AdventHealth, Orlando
Recruiting
Ages 18 and older · All sexes · Updated Jul 3, 2025 · NCT05789433

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.