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Colorectal Cancer clinical trials in Indiana

27 studies for Colorectal Cancer are looking for participants at sites in Indiana.

Cities in Indiana

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

  • Indiana University, Simon Comprehensive Cancer Center, Indianapolis
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07659795

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

  • Franciscan Health, Indianapolis
  • Franciscan Health Mooresville, Mooresville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

  • Community Health Network, Indianapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06663319

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

  • IU Health North Hospital, Carmel
  • Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • Community Health Network, Indianapolis
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

  • Indiana University (IU) School of Medicine, Indianapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

  • Community Health Network, Inc., Indianapolis
  • Hematology Oncology of Indiana, Indianapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

  • Indiana University Simon Comprehensive Cancer Center, Indianapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06625775

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

  • Clinical Study Site, Fort Wayne
  • Clinical Study Site, Indianapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

  • Baptist Health Floyd, New Albany
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT05673148

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Reid Health, Richmond
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Family Communications After Genetic Testing

  • Reid Health, Richmond
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07143487

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

  • Riley Hospital for Children, Indianapolis
RecruitingPhase 1/2
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

  • Community Health Network, Indianapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06586515

Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy

  • Parkview Cancer Institute, Fort Wayne
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT05014399

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

  • Richard L. Roudebush VA Medical Center, Indianapolis
Recruiting
Ages 65 to 82 · All sexes · Updated Aug 13, 2026 · NCT05612347

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

  • Exelixis Clinical Site #4, Indianapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT05176483

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

  • Community Health Network, Indianapolis
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

  • Indiana University, Indianapolis
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06562543

The Food Environment, Microbial Cysteine Metabolism, and Cancer Disparities

  • University Hospital Clinical Research Center, Indianapolis
  • Purdue Clinical Research Center, West Lafayette
Recruiting
Ages 45 to 75 · All sexes · Updated May 14, 2026 · NCT07086833

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

  • Northwest Cancer Centers, Dyer
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

  • Woodland Cancer Care Center, Michigan City
  • Reid Health, Richmond
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

  • Baptist Floyd, New Albany
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.