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Colorectal Cancer clinical trials in Virginia

77 studies for Colorectal Cancer are looking for participants at sites in Virginia.

Cities in Virginia

A Study to Assess Safety and Efficacy of SOT109 in Patients With Advanced Unresectable or Metastatic Colorectal Cancer

  • NEXT Virginia, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07693751

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

  • UVA Comprehensive Cancer Center, Charlottesville
  • Virginia Cancer Specialists, Fairfax
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07659795

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

  • Inova Schar Cancer Institute, Fairfax
  • NEXT Virginia, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06270706

A KRAS Inhibitor in Participants With Advanced Solid Tumors

  • NEXT, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07912593

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

  • University of Virginia, Charlottesville
  • Virginia Cancer Specialists, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07020221

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

  • NEXT Texas LLC - Virginia, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07503808

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

  • University of Virginia Cancer Center, Charlottesville
  • VCU Massey Comprehensive Cancer Center, Richmond
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT06102902

The Vanguard Study: Testing a New Way to Screen for Cancer

  • Sentara Martha Jefferson Hospital, Charlottesville
  • Inova Schar Cancer Institute, Fairfax
  • Inova Fair Oaks Hospital, Fairfax
  • and 5 more
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Nov 6, 2026 · NCT06995898

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

  • NEXT Virginia, Fairfax
RecruitingPhase 1
Ages 18 to 99 · All sexes · Updated Nov 6, 2026 · NCT06983743

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

  • Centra Alan B Pearson Regional Cancer Center, Lynchburg
  • Sovah Health Martinsville, Martinsville
  • Virginia Cancer Institute, Richmond
  • and 4 more
RecruitingPhase 3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07018869

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

  • Inova Schar Cancer Institute, Fairfax
  • Virginia Cancer Specialists, PC, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06324357

A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

  • Virginia Oncology Associates, Newport News
  • Blue Ridge Cancer Care - 300202915, Roanoke
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07549412

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

  • Clinical Study Site, Charlottesville
  • Clinical Study Site, Fairfax
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07228832

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Chesapeake Regional Medical Center, Chesapeake
  • Augusta Health Center for Cancer and Blood Disorders, Fishersville
  • Bon Secours Memorial Regional Medical Center, Mechanicsville
  • and 7 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Nov 4, 2026 · NCT05334069

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

  • Augusta Health Center for Cancer and Blood Disorders, Fishersville
  • Hematology Oncology Associates of Fredericksburg Inc, Fredericksburg
  • Centra Alan B Pearson Regional Cancer Center, Lynchburg
  • and 6 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06418204

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

  • Inova Schar Cancer Institute, Falls Church
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06400472

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

  • NEXT Virginia, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07397338

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

  • Virginia Cancer Specialists, Arlington
  • Inova Schar Cancer Institute Dept of Fairfax Hospital, Fairfax
  • Richmond VA Medical Center, Richmond
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT06662786

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

  • Virginia Cancer Specialists, Arlington
  • Richmond VA Medical Center, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT06750094

Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

  • Virginia Cancer Specialists, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT05856981

A Study to Investigate the Safety and Efficacy of KQB368 as Monotherapy in Participants With Advanced Solid Malignancies

  • NEXT Oncology Virginia, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07542704

Family Communications After Genetic Testing

  • VCU Massey Comprehensive Cancer Center, Richmond
  • VCU Community Memorial Health Center, South Hill
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07143487

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

  • Bon Secours Memorial Regional Medical Center, Mechanicsville
  • Bon Secours Saint Francis Medical Center, Midlothian
  • Bon Secours Saint Mary's Hospital, Richmond
  • and 1 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT05673148

A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

  • NEXT Virginia, LLC, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT06720987

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

  • Oncology & Hematology Associates of Southwest Virginia, Roanoke
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT03526835

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

  • University of Virginia Medical Center, Charlottesville
  • Mary Washington Healthcare, Fredericksburg
  • Hematology Oncology Associates of Fredericksburg Admin, Fredericksburg
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT07284849

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

  • Oncology and Hematology Associates of Southwest Virginia (BRCC) ( Site 0295), Roanoke
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06428409

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

  • NEXT Oncology Virginia, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT07094204

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

  • Virginia Cancer Specialists, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06330064

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

  • Research Site, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06835569

Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic

  • NEXT Oncology Virginia, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT07807345

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

  • Local Institution - 0278, Fairfax
  • Virginia Oncology Associates, Norfolk
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT07221357

A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer

  • Inova Schar Cancer, Fairfax
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06992258

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

  • NEXT Virginia, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT05786924

A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

  • Clinical Trial Site, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT07749586

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

  • Inova Schar Cancer Institute - Fairfax - Innovation Park Drive /ID# 274586, Fairfax
  • Virginia Cancer Specialists - Fairfax /ID# 274339, Fairfax
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT07023289

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

  • Virginia Cancer Specialists, PC, Arlington
  • Oncology & Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care, Blacksburg
  • Virginia Cancer Specialists, PC, Fairfax
  • and 12 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 8, 2026 · NCT07222800

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.