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Epilepsy clinical trials in Ohio

19 studies for Epilepsy are looking for participants at sites in Ohio.

Cities in Ohio

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1

  • Cleveland Clinic, Cleveland
RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07563881

Diagnosing Epilepsy To EffeCT Change

  • University Hospitals Cleveland Medical Center, Clevland
Recruiting
Ages 18 to 75 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07110337

Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

  • University Hospitals Cleveland Medical Center, Cleveland
RecruitingObservational study
Ages 18 to 75 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07110454

Prospective Natural History Study of POLG Disease

  • Akron Children's Hospital, Akron
RecruitingObservational study
All ages ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07775872

A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

  • NeuroScience Research Center, Canton
  • University of Cincinnati, Cincinnati
  • OSU, Columbus
RecruitingPhase 2/3
Ages 18 to 75 ยท All sexes ยท Updated Aug 24, 2026 ยท NCT06132893

AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

  • Cleveland Clinic, Cleveland
  • Ohio State University, Columbus
RecruitingPhase 1/2
Ages 18 to 75 ยท All sexes ยท Updated Aug 24, 2026 ยท NCT06063850

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

  • Summa Health Clinical Research Center, Akron
  • Cleveland Clinic Foundation, Cleveland
  • The Ohio State University, Columbus
  • and 1 more
RecruitingPhase 3
Ages 12 and older ยท All sexes ยท Updated Aug 10, 2026 ยท NCT05667142

Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome

  • Nationwide Children's, Columbus
RecruitingObservational study
Up to age 26 ยท All sexes ยท Updated Aug 6, 2026 ยท NCT05374824

A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

  • Praxis Research Site, Cincinnati
RecruitingPhase 3
1 Day โ€“ 18 Years ยท All sexes ยท Updated Aug 3, 2026 ยท NCT07019922

Epilepsy Journey-An Executive Functioning Intervention for Teens With Epilepsy

  • Cincinnati Children's Hospital Medical Center, Cincinnati
Recruiting
Ages 13 to 17 ยท All sexes ยท Updated Jun 25, 2026 ยท NCT06608966

Readiness Brain Operation Optimization Training (ReBOOT) for Epilepsy Surgery

  • Cleveland Clinic, Cleveland
Recruiting
Ages 18 to 60 ยท All sexes ยท Updated Jun 18, 2026 ยท NCT05992402

Healthy Aging in People With Epilepsy Program

  • Cleveland Clinic, Cleveland
RecruitingHealthy volunteers welcome
Ages 55 to 90 ยท All sexes ยท Updated Jun 12, 2026 ยท NCT06052605

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

  • Cleveland Clinic, Cleveland
  • OhioHealth, Columbus
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated May 14, 2026 ยท NCT05716100

An Examination of Whether Infrared Light Therapy Can Reduce Stress in People With Epilepsy

  • Right Mind Wellness Center, Cincinnati
  • Holly Maggiano, MD, Warren
Recruiting
Ages 18 and older ยท All sexes ยท Updated Apr 23, 2026 ยท NCT07509177

Bridging the Gap: Educating Patients on Social Determinants of Health to Improve Epilepsy Surgery Access and Outcomes

  • Cleveland Clinic, Cleveland
RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Apr 3, 2026 ยท NCT07509190

A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

  • Cleveland Clinic Foundation, Cleveland
RecruitingPhase 2
Ages 18 to 70 ยท All sexes ยท Updated Jan 23, 2026 ยท NCT07219407

Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

  • Cincinnati Children's Hospital Medical Center, Cincinnati
RecruitingPhase 2
1 Day โ€“ 6 Months ยท All sexes ยท Updated Jan 22, 2026 ยท NCT05104983

ESIS in Pediatric DRE

  • Cincinnati Children's Hospital Medical Center, Cincinnati
RecruitingObservational study
Ages 1 to 30 ยท All sexes ยท Updated Dec 23, 2025 ยท NCT05469373

Epilepsy Learning Healthcare System (ELHS)

  • Akron Children's Hospital, Akron
  • Cincinnati Children's Hospital Comprehensive Epilepsy Center (CCHMC), Cincinnati
  • University of Cincinnati Gardner Neuroscience Institute Epilepsy Center, Cincinnati
RecruitingObservational study
All ages ยท All sexes ยท Updated Aug 30, 2024 ยท NCT06265103

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.