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Epilepsy clinical trials in Columbus, OH

5 studies for Epilepsy are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

RecruitingPhase 1/2
  • Ohio State University, Columbus
Ages 18 to 75 · All sexes · Updated Aug 24, 2026 · NCT06063850

A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

RecruitingPhase 2/3
  • OSU, Columbus
Ages 18 to 75 · All sexes · Updated Aug 24, 2026 · NCT06132893

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

RecruitingPhase 3
  • The Ohio State University, Columbus
  • OhioHealth Riverside Methodist Hospital, Columbus
Ages 12 and older · All sexes · Updated Aug 10, 2026 · NCT05667142

Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome

RecruitingObservational study
  • Nationwide Children's, Columbus
Up to age 26 · All sexes · Updated Aug 6, 2026 · NCT05374824

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

RecruitingPhase 3
  • OhioHealth, Columbus
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT05716100

About Epilepsy

Epilepsy is a brain disorder that causes people to have seizures. The seizures may be mild or severe. Learn about causes, diagnosis, and treatment.

More about Epilepsy on MedlinePlus

Epilepsy trials in other cities

Other studies in Columbus

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.