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Head and Neck Squamous Cell Carcinoma clinical trials in Omaha, NE

13 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in and around Omaha (within about 30 miles). Open a study to see who can join and how to contact the study team.

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Nebraska Cancer Specialists, Omaha
  • XCancer, Omaha
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07189871

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

RecruitingPhase 2
  • Nebraska Medicine-Village Pointe, Omaha
  • University of Nebraska Medical Center, Omaha
  • Nebraska Medicine-Bellevue, Bellevue · 9 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • Nebraska Methodist Hospital, Omaha
  • Heartland Oncology and Hematology LLP, Council Bluffs · 4 mi away
  • Methodist Jennie Edmundson Hospital, Council Bluffs · 4 mi away
Ages 18 to 79 · All sexes · Updated Sep 22, 2026 · NCT04671667

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

RecruitingPhase 1/2
  • Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07109726

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

RecruitingPhase 2
  • Nebraska Cancer Specialists/Oncology Hematology West PC - MECC, Omaha
  • Nebraska Methodist Hospital, Omaha
  • Alegent Health Immanuel Medical Center, Omaha
  • and 5 more
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • Oncology Hematology West P.C. dba Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06769698

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

RecruitingPhase 2/3
  • Nebraska Cancer Specialists/Oncology Hematology West PC - MECC, Omaha
  • Nebraska Methodist Hospital, Omaha
  • Heartland Oncology and Hematology LLP, Council Bluffs · 4 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT04333537

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #2, Omaha
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT05176483

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

RecruitingPhase 1/2
  • Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

RecruitingPhase 3
  • GSK Investigational Site, Omaha
Ages 18 and older · All sexes · Updated May 26, 2026 · NCT06256588

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

RecruitingPhase 3
  • Nebraska Methodist Hospital, Omaha
  • Nebraska Medicine-Village Pointe, Omaha
  • University of Nebraska Medical Center, Omaha
  • and 1 more
Ages 18 and older · All sexes · Updated May 11, 2026 · NCT06992427

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

Head and Neck Squamous Cell Carcinoma trials in other cities

Other studies in Omaha

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.