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Non-Small Cell Lung Cancer clinical trials in Omaha, NE

24 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Omaha (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Nebraska Cancer Specialists/Oncology Hematology West PC - MECC, Omaha
  • Nebraska Methodist Hospital, Omaha
  • Nebraska Medicine-Village Pointe, Omaha
  • and 3 more
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04267848

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #2, Omaha
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Nebraska Cancer Specialists, Omaha
  • XCancer, Omaha
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07189871

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

RecruitingPhase 3
  • Nebraska Medicine, Omaha
  • Nebraska Medicine - Village Pointe, Omaha
  • University Of Nebraska Medical Center, Omaha
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07144280

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

RecruitingPhase 3
  • Oncology Hematology West P.C. dba Nebraska Cancer Specialists - Methodist, Omaha
  • Oncology Hematology West, PC dba Nebraska Cancer Specialists - Bergan, Omaha
  • Oncology Hematology West P.C. dba Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06758401

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

RecruitingPhase 2
  • Research Site, Omaha
Ages 18 to 95 · All sexes · Updated Sep 23, 2026 · NCT05061550

A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

RecruitingPhase 2
  • Nebraska Cancer Specialists - Omaha - Wright Street /ID# 271527, Omaha
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06568939

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

RecruitingPhase 2/3
  • Local Institution - 007-590A, Omaha
  • Local Institution - 007-590B, Omaha
  • Nebraska Cancer Specialists - Midwest Cancer Center - Legacy, Omaha
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04613596

Study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in Patients With Solid Tumors

RecruitingPhase 1
  • Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07660055

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

RecruitingPhase 1/2
  • Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

A Multiple Antigen Vaccine (STEMVAC) for the Treatment of Patients With Stage IV Non-Small Cell Lung Cancer

RecruitingPhase 2
  • University of Nebraska Medical Center, Omaha
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT05242965

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

RecruitingPhase 3
  • Nebraska Medicine-Village Pointe, Omaha
  • University of Nebraska Medical Center, Omaha
  • Nebraska Medicine-Bellevue, Bellevue · 9 mi away
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06686771

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

RecruitingPhase 2
  • University of Nebraska Medical Center, Omaha
Ages 18 to 70 · All sexes · Updated Jun 26, 2026 · NCT04614103

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

RecruitingPhase 1
  • Nebraska Cancer Specialists (Midwest Cancer Center - Legacy), Omaha
  • XCancer Omaha / Urology Cancer Center, Omaha
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05283330

Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

RecruitingPhase 2
  • University of Nebraska Medical Center, Omaha
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT04317534

Repositioning Immunotherapy in VetArans With Lung Cancer

RecruitingPhase 2
  • Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE, Omaha
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06275360

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

GEMINI-NSCLC: NSCLC Biomarker Study

RecruitingObservational study
  • Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05236114

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Omaha
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study of the Oral EGFR Inhibitor PLB1004 in Non-Small Cell Lung Cancer

RecruitingPhase 1
  • Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Apr 23, 2025 · NCT06046495

Non-Small Cell Lung Cancer trials in other cities

Other studies in Omaha

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.