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Heart Diseases clinical trials in Massachusetts

17 studies for Heart Diseases are looking for participants at sites in Massachusetts.

Cities in Massachusetts

Transition to KPL-387 Monotherapy Dosing & Administration Study

  • Investigational Site 043, Boston
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 30, 2026 · NCT07288216

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

  • Massachusetts General Hospital, Boston
  • Brigham and Women's Hospital, Boston
  • Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

  • Tufts Medical Center, Boston
  • Massachusetts General Hospital, Boston
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

  • Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489

Clinical Course Of Disease In Participants With FA-CM

  • Boston Children's Hospital, Boston
RecruitingObservational study
Ages 6 and older · All sexes · Updated Sep 2, 2026 · NCT06865482

Randomization of Single vs Multiple Arterial Grafts

  • Baystate Health, Springfield
Recruiting
Ages 18 to 70 · All sexes · Updated Aug 20, 2026 · NCT03217006

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

  • Massachusetts General Hospital, Boston
  • Brigham and Women's Hospital, Boston
  • Boston University (BU) School of Medicine, Boston
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

ELEVATE-HFpEF Clinical Study

  • Tufts Medical Center, Boston
Recruiting
Ages 40 and older · All sexes · Updated Aug 3, 2026 · NCT06678841

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

  • Tufts Medical Center, Boston
  • Boston Medical Center Corporation, Boston
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

  • Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

  • St Elizabeth's Medical Center, Boston
  • Massachusetts General Hospital, Boston
  • Beth Israel Deaconess, Boston
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

  • Baystate Health, Springfield
Recruiting
Ages 18 and older · Women · Updated Apr 1, 2026 · NCT04124120

Lumason® Infusion vs. Bolus Administrations

  • Beth Israel Deaconess Medical Center, Boston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT06400004

PKP2-ACM Natural History Study

  • Boston Children's Hospital, Boston
RecruitingObservational study
Ages 12 and older · All sexes · Updated Feb 27, 2026 · NCT06644742

Personalized Responses to Dietary Composition Trial 3

  • Zoe US Inc., Needham
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 16, 2025 · NCT04735835

PARTNER 3 Trial - Aortic Valve-in-Valve

  • Brigham and Women's Hospital, Boston
Recruiting
All ages · All sexes · Updated May 10, 2024 · NCT03003299

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.