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Heart Diseases clinical trials in Massachusetts

16 studies for Heart Diseases are looking for participants at sites in Massachusetts.

Cities in Massachusetts

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

  • Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06526195

ELEVATE-HFpEF Clinical Study

  • Tufts Medical Center, Boston
Recruiting
Ages 40 and older · All sexes · Updated Nov 3, 2026 · NCT06678841

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

  • Massachusetts General Hospital, Boston
  • Brigham and Women's Hospital, Boston
  • Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT03242642

Transition to KPL-387 Monotherapy Dosing & Administration Study

  • Investigational Site 043, Boston
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Oct 28, 2026 · NCT07288216

Lumason® Infusion vs. Bolus Administrations

  • Beth Israel Deaconess Medical Center, Boston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT06400004

Clinical Course Of Disease In Participants With FA-CM

  • Boston Children's Hospital, Boston
RecruitingObservational study
Ages 6 and older · All sexes · Updated Oct 19, 2026 · NCT06865482

PKP2-ACM Natural History Study

  • Boston Children's Hospital, Boston
RecruitingObservational study
Ages 12 and older · All sexes · Updated Oct 14, 2026 · NCT06644742

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

  • Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489

Randomization of Single vs Multiple Arterial Grafts

  • Baystate Health, Springfield
Recruiting
Ages 18 to 70 · All sexes · Updated Aug 20, 2026 · NCT03217006

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

  • Massachusetts General Hospital, Boston
  • Brigham and Women's Hospital, Boston
  • Boston University (BU) School of Medicine, Boston
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

  • Tufts Medical Center, Boston
  • Boston Medical Center Corporation, Boston
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

  • St Elizabeth's Medical Center, Boston
  • Massachusetts General Hospital, Boston
  • Beth Israel Deaconess, Boston
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

  • Baystate Health, Springfield
Recruiting
Ages 18 and older · Women · Updated Apr 1, 2026 · NCT04124120

Personalized Responses to Dietary Composition Trial 3

  • Zoe US Inc., Needham
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 16, 2025 · NCT04735835

PARTNER 3 Trial - Aortic Valve-in-Valve

  • Brigham and Women's Hospital, Boston
Recruiting
All ages · All sexes · Updated May 10, 2024 · NCT03003299

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.