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Knee Osteoarthritis clinical trials in Illinois
19 studies for Knee Osteoarthritis are looking for participants at sites in Illinois.
Cities in Illinois
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
- Northwestern University, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT05986292Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection
- Bolingbrook Clinic, Bolingbrook
- Hyde Park Clinic, Chicago
- La Grange Clinic, La Grange
- and 2 more
Recruiting
Ages 40 and older · All sexes · Updated Sep 4, 2026 · NCT07804446A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain
- Northwestern University, Chicago
RecruitingPhase 2
Ages 40 and older · All sexes · Updated Sep 4, 2026 · NCT07641517A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee
- Rush Medical College - Division of Rheumatology, Chicago
RecruitingPhase 2
Ages 45 to 80 · All sexes · Updated Aug 25, 2026 · NCT06884865Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection
- Rush University Medical Center, Chicago
Recruiting
Ages 18 to 70 · All sexes · Updated Aug 24, 2026 · NCT05985785AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
- Clinical Investigation Spec Gurnee, Gurnee
- Evanston Premier Hlthcr Res, Skokie
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07509307Genicular Artery Embolization for Knee Osteoarthritis
- Northwestern University, Chicago
Recruiting
Ages 40 to 80 · All sexes · Updated Jul 14, 2026 · NCT07537153MOTION Clinical Trial
- Rush University Medical Center, Chicago
- Genesis Orthopedics & Sports Medicine, Oak Brook
Recruiting
All ages · All sexes · Updated Jul 14, 2026 · NCT06843980geniculaR Artery eMBolization for Knee Osteoarthritis (RAMBO) Registry
- Joint and Vascular Institute, Libertyville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07380906Creation of a Prospective Data Collecting Registry for Genicular Artery Embolization for Arthritis
- University of Chicago Duchossois Center for Advanced Medicine, Chicago
RecruitingObservational study
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT06781463ROAM OA: Functional and Patient Reported Outcomes Wearing a Knee Brace for Unicompartmental OA
- Rush University Medical Center, Chicago
Recruiting
Ages 40 to 85 · All sexes · Updated May 12, 2026 · NCT07224958Brain-Based and Clinical Phenotyping of Pain Pharmacotherapy in Knee Osteoarthritis
- Northwestern University, Chicago
RecruitingPhase 4
Ages 41 and older · All sexes · Updated Apr 30, 2026 · NCT06245109A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients
- Chicago Clinical Research Institute, Inc., Chicago
RecruitingPhase 3
Ages 40 to 80 · All sexes · Updated Apr 29, 2026 · NCT07219771Mechanical Alignment vs Kalipered Kinematic Alignment Total Knee Arthroplasty
- Northwestern Medicine, Chicago
Recruiting
Ages 21 to 79 · All sexes · Updated Mar 24, 2026 · NCT06617871Investigating Patient Satisfaction With Smart Knee Implants
- The University of Chicago Medical Center, Chicago
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Dec 17, 2025 · NCT06968143Ischemic Preconditioning in Osteoarthritis and Back Pain
- Human and Sport Performance Lab, Chicago
Recruiting
Ages 50 and older · All sexes · Updated Nov 17, 2025 · NCT07003113Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis
- University of Chicago, Chicago
RecruitingPhase 2
Ages 40 to 80 · All sexes · Updated May 15, 2025 · NCT06859164Intra-articular Platelet-Rich Plasma Compared With Viscosupplementation in the Treatment of Knee Osteoarthritis
- NorthShore University HealthSystems, Skokie
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Feb 28, 2024 · NCT03491761Physica System Total Knee Replacement Registry Study
- Rush Castle Orthopaedics, Aurora
Recruiting
Ages 22 and older · All sexes · Updated Mar 21, 2023 · NCT03048201From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.