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Leukemia clinical trials recruiting in the U.S.
105 studies for Leukemia are recruiting participants at sites across the United States.
Leukemia is cancer of the white blood cells. There are two types of Leukemias, acute and chronic. Learn about the differences and treatments available.
Cities with the most studies
- Houston, TX31 studies
- Boston, MA27 studies
- New York City, NY21 studies
- Chicago, IL19 studies
- Los Angeles, CA17 studies
- Durham, NC14 studies
- Baldwin Park, CA14 studies
- Nashville, TN13 studies
- Columbus, OH13 studies
- Philadelphia, PA13 studies
- Atlanta, GA12 studies
- Milwaukee, WI12 studies
- Seattle, WA12 studies
- Aurora, CO11 studies
- Birmingham, AL11 studies
- New Haven, CT10 studies
- Edison, NJ10 studies
- Mountain View, CA10 studies
- Cincinnati, OH10 studies
- Orange, CA9 studies
- Dallas, TX9 studies
- Portland, OR9 studies
- Queens, NY9 studies
- Miami, FL9 studies
- Denver, CO8 studies
- Buffalo, NY8 studies
- Clifton, NJ8 studies
- Washington, DC8 studies
- Cedar Rapids, IA7 studies
- Tampa, FL7 studies
- Charlotte, NC7 studies
- San Diego, CA6 studies
- Baltimore, MD6 studies
- Ann Arbor, MI6 studies
- Omaha, NE6 studies
- Detroit, MI5 studies
- Rochester, MN5 studies
- Cleveland, OH5 studies
- Jacksonville, FL5 studies
- St. Louis, MO5 studies
By state
- Alabama11 studies
- Arizona8 studies
- Arkansas3 studies
- California30 studies
- Colorado16 studies
- Connecticut13 studies
- Delaware3 studies
- Florida17 studies
- Georgia13 studies
- Illinois20 studies
- Indiana4 studies
- Iowa8 studies
- Kansas6 studies
- Kentucky6 studies
- Louisiana4 studies
- Maine3 studies
- Maryland12 studies
- Massachusetts29 studies
- Michigan9 studies
- Minnesota9 studies
- Mississippi3 studies
- Missouri7 studies
- Nebraska6 studies
- New Jersey16 studies
- New Mexico4 studies
- New York28 studies
- North Carolina22 studies
- North Dakota3 studies
- Ohio26 studies
- Oklahoma5 studies
- Oregon10 studies
- Pennsylvania16 studies
- Rhode Island5 studies
- South Carolina7 studies
- Tennessee15 studies
- Texas33 studies
- Utah5 studies
- Vermont5 studies
- Virginia8 studies
- Washington12 studies
- West Virginia3 studies
- Wisconsin14 studies
Recently updated studies
CD70.CAR for AML and Other CD70+ Leukemias
RecruitingPhase 1
Up to age 75 ยท All sexes ยท Updated Nov 13, 2026 ยท NCT06345027Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)
RecruitingObservational study
Ages 18 to 110 ยท All sexes ยท Updated Nov 12, 2026 ยท NCT00923507Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 12, 2026 ยท NCT07007312Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP
RecruitingPhase 2
Ages 1 to 18 ยท All sexes ยท Updated Nov 10, 2026 ยท NCT07354074Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 120 ยท All sexes ยท Updated Nov 9, 2026 ยท NCT06856226Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy
RecruitingObservational studyHealthy volunteers welcome
Ages 5 and older ยท All sexes ยท Updated Nov 9, 2026 ยท NCT05237986A Study of CHM-029 in Participants With NPM1 Mutated, KMT2A or NUP98 Rearranged AML
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Nov 6, 2026 ยท NCT07751991cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT05366881A Phase II Study of the Menin Inhibitor Revumenib in Leukemia Associated With Upregulation of HOX Genes
RecruitingPhase 2
Ages 12 and older ยท All sexes ยท Updated Nov 2, 2026 ยท NCT06229912Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia
RecruitingPhase 3
Ages 18 to 71 ยท All sexes ยท Updated Oct 30, 2026 ยท NCT07504458A Randomized Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
RecruitingPhase 2
Ages 18 to 80 ยท All sexes ยท Updated Oct 30, 2026 ยท NCT06520098Mosaic Trial for Stem Cell Transplant Recipients
Recruiting
Ages 18 and older ยท All sexes ยท Updated Oct 30, 2026 ยท NCT06960993A Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive Acute Lymphoblastic Leukemia (ALL)
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Oct 29, 2026 ยท NCT07614022Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Oct 29, 2026 ยท NCT06265584Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution
RecruitingObservational study
Ages 0 to 38 ยท All sexes ยท Updated Oct 29, 2026 ยท NCT06131801Natural History Study of GATA2 Deficiency and Related Disorders
RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 100 ยท All sexes ยท Updated Oct 29, 2026 ยท NCT01905826HEME Home Transfusion Program
Recruiting
Ages 18 and older ยท All sexes ยท Updated Oct 28, 2026 ยท NCT06487247Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
RecruitingObservational study
Ages 18 to 120 ยท All sexes ยท Updated Oct 28, 2026 ยท NCT01137643Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Oct 27, 2026 ยท NCT07356245Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)
RecruitingPhase 1/2
Ages 13 to 90 ยท All sexes ยท Updated Oct 26, 2026 ยท NCT06533579Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
RecruitingObservational study
All ages ยท All sexes ยท Updated Oct 20, 2026 ยท NCT00736749A Study of Revumenib and Mezigdomide in People With Leukemia
RecruitingPhase 1/2
Ages 12 and older ยท All sexes ยท Updated Oct 20, 2026 ยท NCT07356154Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care
Recruiting
Ages 18 and older ยท All sexes ยท Updated Oct 16, 2026 ยท NCT05745285AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
RecruitingPhase 1/2
Ages 12 and older ยท All sexes ยท Updated Oct 13, 2026 ยท NCT06137118A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
RecruitingPhase 1/2
30 Days ยท All sexes ยท Updated Oct 9, 2026 ยท NCT04065399From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.