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Leukemia clinical trials in North Carolina

22 studies for Leukemia are looking for participants at sites in North Carolina.

Cities in North Carolina

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

  • University of North Carolina, Chapel Hill, Chapel Hill
  • Duke University Medical Center, Durham
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07007312

Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia

  • University of North Carolina at Chapel Hill, Chapel Hill
RecruitingPhase 3
Ages 18 to 71 · All sexes · Updated Oct 30, 2026 · NCT07504458

A Randomized Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

  • Durham VA Medical Center, Durham, NC, Durham
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Oct 30, 2026 · NCT06520098

A Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive Acute Lymphoblastic Leukemia (ALL)

  • Atrium Health Levine Cancer, Charlotte
  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT07614022

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill
RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Oct 28, 2026 · NCT01137643

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

  • University of North Carolina at Chapel Hill/ University of North Carolina Medical Center, Chapel Hill
RecruitingPhase 1/2
Ages 13 to 90 · All sexes · Updated Oct 26, 2026 · NCT06533579

Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

  • Mission Hospital Inc-Memorial Campus, Asheville
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Novant Health Presbyterian Medical Center, Charlotte
  • and 3 more
RecruitingObservational study
All ages · All sexes · Updated Oct 20, 2026 · NCT00736749

A Study of Revumenib and Mezigdomide in People With Leukemia

  • University of North Carolina (Data Collection Only), Chapel Hill
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 20, 2026 · NCT07356154

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

  • Duke University Medical Center, Durham
RecruitingPhase 1/2
30 Days · All sexes · Updated Oct 9, 2026 · NCT04065399

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

  • Duke University, Durham
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT04256317

Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

  • Novant Health Clinical Research, Charlotte
  • East Carolina University, Greenville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06824168

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

  • Atrium Health Levine Cancer Center, Charlotte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT06001788

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

  • Levine Children's Hospital, Charlotte
RecruitingPhase 2
Ages 7 to 25 · All sexes · Updated Aug 19, 2026 · NCT05082519

DISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics

  • Lineberger Comphrehensive Cancer Center at University of North Carolina, Chapel Hill
Recruiting
Ages 60 and older · All sexes · Updated Aug 14, 2026 · NCT06296368

Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL)

  • University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, Chapel Hill
RecruitingHealthy volunteers welcome
Ages 6 and older · All sexes · Updated Aug 3, 2026 · NCT07634653

Pre-malignant States to Hematologic Malignancies in Firefighters

  • Levine Cancer Institute, Charlotte
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 49 · All sexes · Updated Jul 13, 2026 · NCT06870760

Factors Affecting Post-transplant Cyclophosphamide (PTCy) Efficacy

  • Levine Cancer Institute, Charlotte
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT03555851

Registry of Older Patients With Cancer

  • Seby B. Jones Cancer Center, Boone
  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill
  • East Carolina University, Greenville
  • and 4 more
RecruitingObservational study
Ages 65 and older · All sexes · Updated Jun 29, 2026 · NCT01137825

Integrated Cancer Repository for Cancer Research

  • Cape Fear Valley Health System, Fayetteville
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

  • Mission Hospital, Asheville
  • Wake Forest University Health Sciences, Winston-Salem
RecruitingObservational study
All ages · All sexes · Updated May 18, 2026 · NCT01790152

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

  • Duke Blood Cancer Center, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 13, 2026 · NCT05735184

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Chapel Hill
  • Massive Bio SYNERGY-AI site, Winston-Salem
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.