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Leukemia clinical trials in Durham, NC

14 studies for Leukemia are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

RecruitingPhase 3
  • Duke University Medical Center, Durham
  • University of North Carolina, Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07007312

Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia

RecruitingPhase 3
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 18 to 71 · All sexes · Updated Oct 30, 2026 · NCT07504458

A Randomized Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

RecruitingPhase 2
  • Durham VA Medical Center, Durham, NC, Durham
Ages 18 to 80 · All sexes · Updated Oct 30, 2026 · NCT06520098

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

RecruitingObservational study
  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill · 10 mi away
Ages 18 to 120 · All sexes · Updated Oct 28, 2026 · NCT01137643

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

RecruitingPhase 1/2
  • University of North Carolina at Chapel Hill/ University of North Carolina Medical Center, Chapel Hill · 10 mi away
Ages 13 to 90 · All sexes · Updated Oct 26, 2026 · NCT06533579

Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

RecruitingObservational study
  • Duke University Medical Center, Durham
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
All ages · All sexes · Updated Oct 20, 2026 · NCT00736749

A Study of Revumenib and Mezigdomide in People With Leukemia

RecruitingPhase 1/2
  • University of North Carolina (Data Collection Only), Chapel Hill · 10 mi away
Ages 12 and older · All sexes · Updated Oct 20, 2026 · NCT07356154

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

RecruitingPhase 1/2
  • Duke University Medical Center, Durham
30 Days · All sexes · Updated Oct 9, 2026 · NCT04065399

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

RecruitingPhase 2/3
  • Duke University, Durham
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT04256317

DISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics

Recruiting
  • Lineberger Comphrehensive Cancer Center at University of North Carolina, Chapel Hill · 10 mi away
Ages 60 and older · All sexes · Updated Aug 14, 2026 · NCT06296368

Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL)

RecruitingHealthy volunteers welcome
  • University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 6 and older · All sexes · Updated Aug 3, 2026 · NCT07634653

Registry of Older Patients With Cancer

RecruitingObservational study
  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill · 10 mi away
Ages 65 and older · All sexes · Updated Jun 29, 2026 · NCT01137825

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

RecruitingPhase 1
  • Duke Blood Cancer Center, Durham
Ages 18 and older · All sexes · Updated Mar 13, 2026 · NCT05735184

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Chapel Hill · 10 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Leukemia

Leukemia is cancer of the white blood cells. There are two types of Leukemias, acute and chronic. Learn about the differences and treatments available.

More about Leukemia on MedlinePlus

Leukemia trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.