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Leukemia clinical trials in Chicago, IL

19 studies for Leukemia are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

RecruitingPhase 3
  • Northwestern, Chicago
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07007312

Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP

RecruitingPhase 2
  • Ann and Robert H Lurie Childs Hosp, Chicago
Ages 1 to 18 · All sexes · Updated Nov 10, 2026 · NCT07354074

Mosaic Trial for Stem Cell Transplant Recipients

Recruiting
  • Northwestern University Feinberg School of Medicine, Chicago
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT06960993

Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

RecruitingObservational study
  • Lurie Children's Hospital-Chicago, Chicago
  • University of Illinois, Chicago
  • University of Chicago Comprehensive Cancer Center, Chicago
All ages · All sexes · Updated Oct 20, 2026 · NCT00736749

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

Recruiting
  • University of Chicago Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT05745285

AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia

RecruitingPhase 1/2
  • Research Site, Chicago
Ages 12 and older · All sexes · Updated Oct 13, 2026 · NCT06137118

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

RecruitingPhase 1/2
  • The University of Chicago Medical Center, Chicago
30 Days · All sexes · Updated Oct 9, 2026 · NCT04065399

Study of Allo-QuadCAR01-T, an Allogeneic CAR-T Targeting CD19/CD20, in Patients With Relapsed or Refractory B-Cell Malignancies

RecruitingPhase 1/2
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07284433

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

RecruitingPhase 1
  • Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT06001788

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

RecruitingPhase 2
  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Ages 7 to 25 · All sexes · Updated Aug 19, 2026 · NCT05082519

Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)

RecruitingPhase 2
  • University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Jun 5, 2026 · NCT04747912

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

RecruitingObservational study
  • Lurie Children's Hospital-Chicago, Chicago
All ages · All sexes · Updated May 18, 2026 · NCT01790152

The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies

RecruitingPhase 1/2
  • University of Illinois at Chicago Cancer Center, Chicago
Ages 12 to 95 · All sexes · Updated Apr 15, 2026 · NCT04329728

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

RecruitingPhase 1
  • Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Mar 13, 2026 · NCT05735184

Spiritual Care Intervention in Adult Patients Diagnosed With Acute Leukemia

Recruiting
  • UChicago Medicine Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Mar 4, 2026 · NCT07405424

CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL

RecruitingPhase 1/2
  • University of Chicago Medicine Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Mar 4, 2026 · NCT07294677

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Chicago
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

RecruitingPhase 1
  • Northwestern Medicine - Northwestern Memorial Hospital Galter Pavilion, Chicago
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT06501196

About Leukemia

Leukemia is cancer of the white blood cells. There are two types of Leukemias, acute and chronic. Learn about the differences and treatments available.

More about Leukemia on MedlinePlus

Leukemia trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.