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Long COVID clinical trials in Illinois

14 studies for Long COVID are looking for participants at sites in Illinois.

Cities in Illinois

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1283 in Participants ≥6 Months to <12 Years of Age

  • Eagle Clinical Research, LLC, Chicago
RecruitingPhase 2Healthy volunteers welcome
6 Months – 11 Years · All sexes · Updated Nov 9, 2026 · NCT07808697

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

  • Rush University Medical Center ( Site 3748), Chicago
  • Duly Health and Care ( Site 3799), Lombard
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT06667700

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

  • University of Illinois Health, Chicago
RecruitingPhase 3
28 Days · All sexes · Updated Nov 4, 2026 · NCT02735707

Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

  • Research Site, Evanston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT05624450

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

  • Endeavor Health Evanston Hospital, Evanston
  • Koch Family Medicine, Morton
  • Endeavor Health Clinical Trials Center, Skokie
  • and 1 more
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Oct 15, 2026 · NCT06679140

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

  • Northwestern Memorial Hospital, Chicago
  • Northwestern University Feinberg School of Medicine, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT07013474

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

  • Illinois Research Network (ILLInet), University of Illinois Chicago, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06631287

Dime La VerDAD: Verify, Debunk, and Disseminate

  • University of Chicago, Chicago
RecruitingHealthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Aug 26, 2026 · NCT06417762

Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
RecruitingPhase 3
All ages · All sexes · Updated Jun 23, 2026 · NCT03808922

Cognitive-Sensorimotor Function in Long-COVID

  • Jesse Brown VA Medical Center, Chicago, IL, Chicago
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT06850350

Dysbiosis & Long COVID

  • The University of Chicago, Chicago
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Mar 2, 2026 · NCT06825819

A Pilot Clinical Evaluation of Astepro® Nasal Spray for Management of Early SARS-CoV-2 Infection

  • University of Chicago, Chicago
RecruitingPhase 4Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 10, 2025 · NCT06008860

Convalescent Plasma as a Possible Treatment for COVID-19

  • University of Illinois at Chicago, Chicago
RecruitingPhase 2
Ages 40 and older · All sexes · Updated Jun 22, 2020 · NCT04442191

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.