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Lymphoma clinical trials in Chicago, IL

20 studies for Lymphoma are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma

RecruitingPhase 2
  • Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07015242

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

RecruitingPhase 1/2
  • Lurie Children's Hospital-Chicago, Chicago
  • University of Chicago Comprehensive Cancer Center, Chicago
12 Months – 21 Years · All sexes · Updated Sep 11, 2026 · NCT04870944

A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

RecruitingPhase 1
  • University of Illinois Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06624085

Study of Allo-QuadCAR01-T, an Allogeneic CAR-T Targeting CD19/CD20, in Patients With Relapsed or Refractory B-Cell Malignancies

RecruitingPhase 1/2
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07284433

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

RecruitingPhase 1/2
  • University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04104776

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

RecruitingPhase 1
  • The David and Etta Jonas Center for Cellular Therapy, Chicago
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06528301

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

RecruitingPhase 3
  • Northwestern, Chicago
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT07188558

Mosaic Trial for Stem Cell Transplant Recipients

Recruiting
  • Northwestern University Feinberg School of Medicine, Chicago
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT06960993

DALY II USA/ MB-CART2019.1 for DLBCL

RecruitingPhase 2
  • Robert H Lurie Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT04792489

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

RecruitingPhase 1/2
  • Call for Information (Investigational Site 0024), Chicago
6 Months – 17 Years · All sexes · Updated Jul 6, 2026 · NCT02332668

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

RecruitingPhase 1
  • Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT05131022

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

RecruitingObservational study
  • Lurie Children's Hospital-Chicago, Chicago
All ages · All sexes · Updated May 18, 2026 · NCT01790152

CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

RecruitingPhase 1/2
  • Northwestern Memorial Hospital, Chicago
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT03328078

The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies

RecruitingPhase 1/2
  • University of Illinois at Chicago Cancer Center, Chicago
Ages 12 to 95 · All sexes · Updated Apr 15, 2026 · NCT04329728

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

RecruitingPhase 1
  • The University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT04830137

CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL

RecruitingPhase 1/2
  • University of Chicago Medicine Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Mar 4, 2026 · NCT07294677

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

Recruiting
  • University of Chicago Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Feb 20, 2026 · NCT05745285

Avo In R/R And Previously Untreated MCL

RecruitingPhase 1/2
  • University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT04855695

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

RecruitingPhase 1
  • Northwestern University, Robert H. Lurie Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Sep 22, 2025 · NCT04234048

About Lymphoma

Lymphoma is a cancer affecting the immune system. Hodgkins Lymphoma and Non Hodgkins Lymphoma are types of lymphoma. Learn about symptoms and treatments.

More about Lymphoma on MedlinePlus

Lymphoma trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.