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Obesity clinical trials in Chicago, IL
42 studies for Obesity are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes
RecruitingPhase 2
- Charter Research LLC - Chicago, Chicago
- Flourish Research - Chicago, Chicago
Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities
RecruitingPhase 2
- Great Lakes Clinical Trials - West Wilson Avenue /ID# 282378, Chicago
AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight
RecruitingPhase 3
- Great Lakes Clinical Trials, Chicago
A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide
RecruitingPhase 3
- Chicago Research Center, Inc, Chicago
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
RecruitingPhase 3
- Cedar Crosse Research Center, Chicago
- Northwestern University, Chicago
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
RecruitingPhase 3
- Research Site, Chicago
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
RecruitingPhase 3
- Ann and Robert Lurie Children's Hospital of Chicago, Chicago
- University of Illinois at Chicago, Chicago
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
RecruitingPhase 3
- Rush University Medical Center, Chicago
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
RecruitingPhase 3
- Rush University Medical Center, Chicago
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
RecruitingPhase 2
- Great Lakes Clinical Trials - Ravenswood, Chicago
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
RecruitingPhase 3
- Great Lakes Clinical Trials - Ravenswood, Chicago
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee
RecruitingPhase 3
- Northwestern University, Chicago
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
RecruitingPhase 3
- Research Site, Chicago
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
RecruitingPhase 3
- Great Lakes Clinical Trials - Ravenswood, Chicago
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
RecruitingPhase 3
- Eagle Clinical Research, Chicago
- University of Chicago, Chicago
AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
RecruitingPhase 3
- University Of Chicago, Chicago
AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
RecruitingPhase 3
- Chicago Research Center, Inc, Chicago
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
RecruitingPhase 2
- Great Lakes Clinical Trials - Ravenswood, Chicago
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
RecruitingPhase 3
- Flourish Research - Great Lakes Clinical Trials, Chicago
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
RecruitingPhase 3
- Kailera Clinical Site, Chicago
BRIDGE & Friends Trial
RecruitingHealthy volunteers welcome
- University of Illinois Chicago, Chicago
Assess the Effects of Replacing Foods High in Refined Carbohydrates With Avocado on Biomarkers of Inflammation.
RecruitingHealthy volunteers welcome
- Illinois Institute of Technology, Chicago
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
RecruitingPhase 3
- Research Site, Chicago
Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL
RecruitingPhase 2
- Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
RecruitingPhase 3
- Chicago Clinical Research Institute INC, Chicago
- Univer Of Illinois at Chicago, Chicago
- Eagle Clinical Research, Chicago
Digital InteGrated Behavioral treatmeNt for Comorbid obesITy and deprEssion Among Racial and Ethnic Adults Age 50 and Older
Recruiting
- Department of Medicine, Vitoux Program on Aging and Prevention, Chicago
Role of Adiposomes in Endothelial Dysfunction
Recruiting
- University of Illinois at Chicago, Chicago
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
RecruitingPhase 3
- ACCOMPLISH-1 Research Site, Chicago
Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention
Recruiting
- Jesse Brown VA Medical Center, Chicago
FIM+DASH: Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control
RecruitingPhase 2
- Mile Square Health Center Chicago, Chicago
- Mile Square Health Center - Auburn Gresham, Chicago
- Mile Square Health Center - Englewood, Chicago
- and 1 more
Better Lifestyle Counseling for African American Women During Pregnancy
Recruiting
- University of Illinois at Chicago, Chicago
- University of Illinois at Chicago, Chicago
PRImary Care Strategies for Weight Management (PRISM) Study
Recruiting
- Rush University Medical Center, Chicago
Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients
Recruiting
- Prentice Women's Hospital, Chicago
Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors
Recruiting
- Northwestern University-Feinberg School of Medicine, Chicago
EAT: A Reliable Eating Assessment Technology for Free-living Individuals
RecruitingHealthy volunteers welcome
- Northwestern University, Chicago
RemI for Post-Bariatric Surgery Weight Regain
RecruitingHealthy volunteers welcome
- Rush University, Chicago
People With Multiple Sclerosis Treated With Ocrelizumab and GLP-1 Agonists
RecruitingObservational study
- Northwestern Memorial Hospital, Chicago
Predictors of Behavioral Obesity Treatment Outcomes
RecruitingHealthy volunteers welcome
- Rush University Medical Center, Chicago
A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment
RecruitingPhase 1/2Healthy volunteers welcome
- Ann and Robert H. Lurie Children's Hospital of Chicago (Part C and Part D), Chicago
Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial Fibrillation
RecruitingPhase 3
- University of Chicago, Chicago
Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors
Recruiting
- University of Illinois Chicago, Chicago
DNA Methylation and Vascular Function
RecruitingHealthy volunteers welcome
- University of Illinois at Chicago, Chicago
About Obesity
Read about the causes of obesity and find out what you can do to decrease your risk of its associated health issues.
More about Obesity on MedlinePlus
Obesity trials in other cities
- Houston, TX44 studies
- New York City, NY40 studies
- San Antonio, TX39 studies
- Washington, DC33 studies
- Dallas, TX31 studies
- Boston, MA29 studies
- Orlando, FL29 studies
- Las Vegas, NV27 studies
- Miami, FL27 studies
- Baltimore, MD25 studies
- Jacksonville, FL25 studies
- Atlanta, GA25 studies
Other studies in Chicago
- Non-Small Cell Lung Cancer62 studies
- Breast Cancer58 studies
- Cancer (all types)53 studies
- Metastatic Cancer45 studies
- Prostate Cancer45 studies
- Lung Cancer41 studies
- Ovarian Cancer36 studies
- Stroke35 studies
- Heart Failure32 studies
- Colorectal Cancer32 studies
- Overweight28 studies
- Acute Myeloid Leukemia27 studies
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.