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Melanoma clinical trials in Ann Arbor, MI

12 studies for Melanoma are looking for participants at sites in and around Ann Arbor (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

RecruitingPhase 3
  • University of Michigan, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06246916

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

RecruitingPhase 2
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • University of Michigan Rogel Cancer Center, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • and 5 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

RecruitingPhase 2
  • Local Institution - 0119, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

RecruitingPhase 2
  • University of Michigan Comprehensive Cancer Center, Ann Arbor
  • University of Michigan - Brighton Center for Specialty Care, Brighton · 18 mi away
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • and 4 more
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • C S Mott Children's Hospital, Ann Arbor
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • C S Mott Children's Hospital, Ann Arbor
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

Neoadjuvant Darovasertib in Primary Uveal Melanoma

RecruitingPhase 3
  • W Kellogg Eye Center, Ann Arbor
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07015190

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Ann Arbor
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Excision of Lymph Node Trial (EXCILYNT) (Mel69)

Recruiting
  • University of Michigan, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 17, 2025 · NCT05839912

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Recruiting
  • University of Michigan Medical Center, Ann Arbor
  • University of Michigan - Brighton Center for Specialty Care, Brighton · 18 mi away
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Ann Arbor

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.