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Melanoma clinical trials in Dallas, TX

20 studies for Melanoma are looking for participants at sites in and around Dallas (within about 30 miles). Open a study to see who can join and how to contact the study team.

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Dallas
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

RecruitingPhase 3
  • Texas Oncology - Medical City, Dallas
  • Texas Oncology, Dallas
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06246916

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

RecruitingPhase 1/2
  • Baylor, Scott and White Research Institute, Dallas
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • UT Southwestern Medical Center, Dallas
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma

RecruitingPhase 1/2
  • UT Southwestern, Dallas
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07288112

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

RecruitingPhase 1/2
  • Texas Oncology - Dallas SCRI, Dallas
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07287917

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Medical City Dallas Hospital, Dallas
  • UT Southwestern/Simmons Cancer Center-Dallas, Dallas
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

RecruitingPhase 1/2
  • Texas Oncology, P.A., Dallas
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

RecruitingPhase 1/2
  • Call for Information (Investigational Site 0054), Dallas
6 Months – 17 Years · All sexes · Updated Jul 6, 2026 · NCT02332668

Identification of Metabolic Phenotypes Associated With Melanoma Metastasis

RecruitingObservational study
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06400550

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Mary Crowley Cancer Research, Dallas
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Neoadjuvant Darovasertib in Primary Uveal Melanoma

RecruitingPhase 3
  • Texas Retina Associates - Dallas, Dallas
  • University of Texas Southwestern Medical Center-5323 Harry Hines Blvd, Dallas
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07015190

A Study of VET3-TGI in Patients With Solid Tumors

RecruitingPhase 1
  • Mary Crowley Cancer Research, Dallas
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT06444815

A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors

RecruitingPhase 1/2
  • Research Site, Dallas
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06956690

A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Dallas, Dallas
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT07317505

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 120, Dallas
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Dallas
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Mary Crowley Cancer Research, Dallas
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT04370587

A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology, Dallas, Dallas
Ages 18 and older · All sexes · Updated Jan 26, 2024 · NCT05746897

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Dallas

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.